Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9122157 | 0.92 | KMT2A (0.56) | KMT2AGAAMAPK1POLBMAPT | |
| SCHEMBL9320727 | 0.87 | KMT2A (0.60) | KMT2AGAAMAPK1POLBMAPT | |
| SCHEMBL9912233 | 0.86 | KMT2A (0.59) | KMT2AGAAMAPK1POLBMAPT | |
| SCHEMBL12250691 | 0.84 | KMT2A (0.61) | KMT2AGAAMAPK1POLBMAPT | |
| SCHEMBL7892555 | 0.83 | KMT2A (0.56) | KMT2AGAAMAPK1POLBMAPT | |
| SCHEMBL11128406 | 0.82 | KMT2A (0.62) | KMT2AGAAMAPK1POLBMAPT | |
| SCHEMBL654293 | 0.82 | LMNA (0.69) | KMT2AGAAMAPK1POLBMAPT | |
| SCHEMBL8976610 | 0.82 | KMT2A (0.62) | KMT2AGAAMAPK1POLBMAPT | |
| SCHEMBL30024728 | 0.82 | LMNA (0.69) | KMT2AGAAMAPK1POLBMAPT | |
| SCHEMBL6309076 | 0.81 | CYP3A4 (0.61) | KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286905-A | Heating hydrogen halide salt of phenoxyalkylamine with dicyandiamide in paraffinic hydrocarbon solvent | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0492615-A1 | Process for producing biguanide derivative | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-07-01 | — | — | EP | disclosed |