Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.56 |
| ▸ | MITF | O75030 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GMPS | P49915 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27861904 | 0.86 | KMT2A (0.60) | ALDH1A1HTTMITFMAPK1POLB | |
| SCHEMBL2113107 | 0.86 | ALDH1A1 (0.60) | ALDH1A1HTTMITFMAPK1POLB | |
| SCHEMBL31022670 | 0.86 | ALDH1A1 (0.60) | ALDH1A1HTTMITFMAPK1POLB | |
| SCHEMBL11802189 | 0.85 | ALDH1A1 (0.67) | ALDH1A1HTTMITFMAPK1POLB | |
| Hydrochloric Acid SCHEMBL9320149 | 0.85 | ALDH1A1 (0.59) | ALDH1A1HTTMITFMAPK1POLB | |
| SCHEMBL8689535 | 0.85 | MEN1 (0.71) | ALDH1A1HTTMITFMAPK1POLB | |
| SCHEMBL31703422 | 0.85 | MEN1 (0.71) | ALDH1A1HTTMITFMAPK1POLB | |
| SCHEMBL10913181 | 0.82 | ALDH1A1 (0.64) | ALDH1A1HTTMITFMAPK1POLB | |
| SCHEMBL7194474 | 0.80 | GMPS (0.57) | ALDH1A1HTTMITFMAPK1POLB | |
| SCHEMBL2328579 | 0.79 | ALDH1A1 (0.59) | ALDH1A1POLBKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286728-A | Amino-substituted piperazine derivatives | CIBA-GEIGY CORPORATION (US) | 1994-02-15 | — | — | US | disclosed |
| US-4132803-A | TOPICAL APPLICATION TO TRACHEA | MEAD JOHNSON & COMPANY (US) | 1979-01-02 | — | — | US | disclosed |
| US-4093739-A | Mercaptoacylamidobenzoyl glycine and mucolytic process | MEAD JOHNSON & COMPANY (US) | 1978-06-06 | — | — | US | disclosed |