SCHEMBL9320144

SCHEMBL9320144

O=c1ccsn1Cc1ccccc1Cl

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.64
G6PD P11413 2/20 0.64
HPGD P15428 2/20 0.64
ALOX15 P16050 2/20 0.64
HSD17B10 Q99714 2/20 0.64
MAPT P10636 2/20 0.64
HTT P42858 2/20 0.64
PKM P14618 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
SMN1; SMN2 Q16637 2/20 0.49
CYP3A4 P08684 2/20 0.44
CYP2A13 Q16696 1/20 0.44
TP53 P04637 1/20 0.44
HSP90AA1 P07900 1/20 0.44
TSHR P16473 1/20 0.44
HIF1A Q16665 1/20 0.44
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
POLB P06746 2/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1879713 0.78 ALDH1A1 (1.00) ALDH1A1G6PDHPGDALOX15HSD17B10
Hydrochloric Acid SCHEMBL11708755 0.75 ALDH1A1 (0.93) ALDH1A1G6PDHPGDALOX15HSD17B10
Hydrochloric Acid SCHEMBL11708748 0.75 ALDH1A1 (0.93) ALDH1A1G6PDHPGDALOX15HSD17B10
SCHEMBL2808252 0.73 ALDH1A1 (0.70) ALDH1A1G6PDHPGDALOX15HSD17B10
SCHEMBL9321009 0.71 ALDH1A1 (0.62) ALDH1A1G6PDHPGDALOX15HSD17B10
SCHEMBL5593782 0.71 ALDH1A1 (0.53) ALDH1A1G6PDHPGDALOX15HSD17B10
Chloroacetic Acid SCHEMBL9321136 0.70 ALDH1A1 (0.81) ALDH1A1G6PDHPGDALOX15HSD17B10
SCHEMBL14640597 0.69 ALDH1A1 (0.54) ALDH1A1G6PDHPGDALOX15HSD17B10
SCHEMBL7695911 0.69 ALDH1A1 (0.78) ALDH1A1G6PDHPGDALOX15HSD17B10
SCHEMBL9322109 0.68 ALDH1A1 (0.68) ALDH1A1G6PDHPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0331319-B1 Method for the formation of images KONISHIROKU PHOTO IND (JP) 1994-01-26 EP disclosed
US-H1090-H High contrast; hydrazide, isothizolone, bromonitroalcohol KONICA CORPORATION (JP) 1992-08-04 US disclosed
EP-0356801-A1 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1990-03-07 EP disclosed
EP-0331319-A1 Method for the formation of images KONICA CORPORATION (JP) 1989-09-06 EP disclosed
EP-0090584-B1 LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1986-12-03 EP disclosed
US-4490462-A CONTAINING ISOTHIAZOLIN-3-ONE MICROBIOCIDE OR FUNGICIDE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-12-25 US disclosed
EP-0090584-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1983-10-05 EP disclosed