SCHEMBL2808252

SCHEMBL2808252

O=c1ccsn1Cc1ccc(Cl)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.70
MAPT P10636 3/20 0.70
G6PD P11413 2/20 0.70
HPGD P15428 2/20 0.70
ALOX15 P16050 2/20 0.70
HSD17B10 Q99714 2/20 0.70
PKM P14618 1/20 0.70
HTT P42858 1/20 0.70
TDP1 Q9NUW8 1/20 0.70
TP53 P04637 1/20 0.47
HSP90AA1 P07900 1/20 0.47
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
HIF1A Q16665 1/20 0.47
KAT2B Q92831 2/20 0.45
EP300 Q09472 1/20 0.45
CREBBP Q92793 1/20 0.45
KAT2A Q92830 1/20 0.45
THRB P10828 1/20 0.40
PDE1B Q01064 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3655957 0.89 ALDH1A1 (0.57) ALDH1A1MAPTG6PDHPGDALOX15
SCHEMBL7628912 0.85 ALDH1A1 (0.51) ALDH1A1MAPTG6PDHPGDALOX15
SCHEMBL9322109 0.83 ALDH1A1 (0.68) ALDH1A1MAPTG6PDHPGDALOX15
SCHEMBL9132689 0.83 ALDH1A1 (0.68) ALDH1A1MAPTG6PDHPGDALOX15
SCHEMBL5593583 0.83 ALDH1A1 (0.68) ALDH1A1MAPTG6PDHPGDALOX15
SCHEMBL1879713 0.82 ALDH1A1 (1.00) ALDH1A1MAPTG6PDHPGDALOX15
SCHEMBL9321009 0.82 ALDH1A1 (0.62) ALDH1A1MAPTG6PDHPGDALOX15
SCHEMBL7307539 0.81 MAPT (0.70) ALDH1A1MAPTG6PDHPGDALOX15
Hydrochloric Acid SCHEMBL9320078 0.81 ALDH1A1 (0.96) ALDH1A1MAPTG6PDHPGDALOX15
Hydrochloric Acid SCHEMBL11708748 0.79 ALDH1A1 (0.93) ALDH1A1MAPTG6PDHPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020128311-A1 Halocyanoacetamide antimicrobial compositions GIRONDA KEVIN F (US) 2002-09-12 US claimed
EP-0540213-B1 Bromate as an inhibitor of nitrosamine formation in nitrate stabilized isothiazolones ROHM & HAAS (US) 1996-10-30 EP claimed
EP-0542408-B1 Bromate stabilizers for 3-isothiazolones ROHM & HAAS (US) 1996-01-10 EP claimed
EP-0542408-A1 Bromate stabilizers for 3-isothiazolones ROHM AND HAAS COMPANY (US) 1993-05-19 EP claimed
EP-0540213-A1 Bromate as an inhibitor of nitrosamine formation in nitrate stabilized isothiazolones ROHM AND HAAS COMPANY (US) 1993-05-05 EP claimed
EP-2207416-B1 ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM IMERYS FILTRATION MINERALS INC (US) 2018-11-07 EP disclosed
US-20100239679-A1 ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM WORLD MINERALS, INC. (US) 2010-09-23 US disclosed
EP-2207416-A1 ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM World Minerals, Inc. (US) 2010-07-21 EP disclosed
WO-2009045941-A1 ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM WORLD MINERALS, INC. (US) 2009-04-09 WO disclosed
US-20060276339-A1 Methods and compositions for increasing the efficacy of biologically-active ingredients BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2006-12-07 US disclosed
US-20020128311-A1 Halocyanoacetamide antimicrobial compositions GIRONDA KEVIN F (US) 2002-09-12 US disclosed
EP-1219172-A1 Halocyanoacetamide antimicrobial compositions ROHM AND HAAS COMPANY (US) 2002-07-03 EP disclosed
EP-0410726-A1 S-substituted beta-thioacrylamides and their use as microbicides ROHM AND HAAS COMPANY (US) 1991-01-30 EP disclosed
EP-0356801-A1 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1990-03-07 EP disclosed
EP-0331319-A1 Method for the formation of images KONICA CORPORATION (JP) 1989-09-06 EP disclosed
EP-0090584-B1 LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1986-12-03 EP disclosed
US-4490462-A CONTAINING ISOTHIAZOLIN-3-ONE MICROBIOCIDE OR FUNGICIDE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-12-25 US disclosed
EP-0090584-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1983-10-05 EP disclosed
US-4165318-A AGAINST CHEMICAL DECOMPOSITION OF THE 3-ISOTHIAZOLONE MILDEW CONTROLLING AGENT ROHM AND HAAS COMPANY (US) 1979-08-21 US disclosed
US-4129448-A A 3-ISOTHIAZOLONE ROHM AND HAAS COMPANY (US) 1978-12-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060276339-A1 Methods and compositions for increasing the efficacy of biologically-active ingredients ENPP1, ENPP3, SMPD1 ALDH1A1 2504/4885MAPT 4463/4885G6PD 271/4885
US-20020128311-A1 Halocyanoacetamide antimicrobial compositions HDHD5, DGKI, DAGLA ALDH1A1 2941/4885MAPT 3278/4885G6PD 3211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.