Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9320200 | 0.85 | ALDH1A1 (0.58) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL2680891 | 0.81 | MEN1 (0.79) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL21383161 | 0.79 | ALDH1A1 (0.69) | ALDH1A1MAPTMEN1KMT2AHDAC1 | |
| SCHEMBL7282859 | 0.78 | ALDH1A1 (0.68) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL7291409 | 0.74 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL31492222 | 0.74 | ALDH1A1 (0.67) | ALDH1A1MEN1POLBKMT2AHDAC1 | |
| SCHEMBL4006377 | 0.74 | ALDH1A1 (0.67) | ALDH1A1MEN1POLBKMT2AHDAC1 | |
| SCHEMBL30021051 | 0.74 | TDP1 (0.61) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL31703290 | 0.74 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL249982 | 0.73 | PDK1 (0.54) | ALDH1A1MAPTMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286728-A | Amino-substituted piperazine derivatives | CIBA-GEIGY CORPORATION (US) | 1994-02-15 | — | — | US | disclosed |