Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321687 | 1.00 | SIGMAR1 (0.50) | SIGMAR1S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL9321708 | 0.91 | SIGMAR1 (0.53) | SIGMAR1S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL9321710 | 0.91 | SIGMAR1 (0.53) | SIGMAR1S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL10704410 | 0.87 | SIGMAR1 (0.53) | SIGMAR1S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL11099976 | 0.83 | CYP3A4 (0.56) | — | |
| SCHEMBL10701856 | 0.82 | SIGMAR1 (0.49) | SIGMAR1S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL11105725 | 0.82 | CYP3A4 (0.54) | — | |
| SCHEMBL9320940 | 0.77 | SIGMAR1 (0.49) | SIGMAR1S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL9320218 | 0.74 | L3MBTL1 (0.61) | S1PR2S1PR1S1PR3LPAR2EPHX2 | |
| SCHEMBL9323087 | 0.74 | EPHX2 (0.78) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282127-B1 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | PROCTER & GAMBLE (US) | 1994-02-02 | — | — | EP | disclosed |
| US-5099030-A | Phenols or phenolic ethers | THE PROCTER & GAMBLE COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-5045565-A | Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain | THE PROCTER & GAMBLE COMPANY (US) | 1991-09-03 | — | — | US | disclosed |