Prochloraz

Prochloraz

SCHEMBL9320347

CCCN(CCOc1c(Cl)cc(Cl)cc1Cl)C(=O)n1ccnc1.COC(=O)c1ccc(O)cc1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.78
ADRB2 P07550 5/20 0.38
ADRB1 P08588 5/20 0.38
ADRB3 P13945 5/20 0.38
HTT P42858 1/20 0.37
CYP26A1 O43174 1/20 0.35
CYP3A4 P08684 1/20 0.35
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA12 O43570 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34
ALDH1A1 P00352 3/20 0.34
POLB P06746 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
ACLY P53396 1/20 0.33
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prochloraz SCHEMBL8180955 0.93 AHR (0.90) AHRADRB2ADRB1ADRB3KDM4E
Prochloraz SCHEMBL9316172 0.89 AHR (0.76) AHRADRB2ADRB1ADRB3CYP26A1
Prochloraz SCHEMBL4745585 0.88 AHR (0.85) AHRADRB2ADRB1ADRB3KDM4E
Prochloraz SCHEMBL34675 0.88 AHR (1.00) AHRADRB2ADRB1ADRB3KDM4E
Prochloraz SCHEMBL22242 0.88 AHR (1.00) AHRADRB2ADRB1ADRB3KDM4E
Prochloraz SCHEMBL30468212 0.87 AHR (0.94) AHRADRB2ADRB1ADRB3KDM4E
Prochloraz SCHEMBL31567753 0.87 AHR (0.94) AHRADRB2ADRB1ADRB3KDM4E
Prochloraz SCHEMBL11375792 0.87 AHR (0.98) AHRADRB2ADRB1ADRB3KDM4E
Prochloraz SCHEMBL12611119 0.87 AHR (0.98) AHRADRB2ADRB1ADRB3KDM4E
Prochloraz SCHEMBL9371936 0.87 AHR (0.98) AHRADRB2ADRB1ADRB3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3256520-B1 MODELLING COMPOUND DELTA OF SWEDEN AB (SE) 2023-06-21 EP disclosed
US-11274193-B2 Modelling compound DELTA OF SWEDEN AB (SE) 2022-03-15 US disclosed
US-20180030247-A1 MODELLING COMPOUND DELTA OF SWEDEN AB (SE) 2018-02-01 US disclosed
EP-3256520-A1 MODELLING COMPOUND Ramlat Ltd. (MT) 2017-12-20 EP disclosed
WO-2016128582-A1 MODELLING COMPOUND RAMLAT LIMITED (MT) 2016-08-18 WO disclosed
EP-0338495-B1 Roof or wall covering ROLAND WERKE DACHBAUSTOFFE UND (DE) 1994-02-02 EP disclosed
US-5088249-A ROOF COVERING OR WALL COVERING ROLAND-WERKE DACHBAUSTOFFE UND BAUCHEMIE GMBH & CO. KG (DE) 1992-02-18 US disclosed
EP-0338495-A2 Roof or wall covering Roland-Werke Dachbaustoffe und Bauchemie GmbH & Co. KG (DE) 1989-10-25 EP disclosed