Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436638 | 0.79 | GPR35 (0.57) | GPR35LTB4RCYSLTR2CYSLTR1BID | |
| SCHEMBL8516407 | 0.79 | GPR35 (0.57) | GPR35LTB4RCYSLTR2CYSLTR1BID | |
| SCHEMBL17353545 | 0.79 | GPR35 (0.57) | GPR35LTB4RCYSLTR2CYSLTR1BID | |
| SCHEMBL7474906 | 0.79 | GPR35 (0.57) | GPR35LTB4RCYSLTR2CYSLTR1BID | |
| SCHEMBL6928575 | 0.78 | GPR35 (0.46) | MAPK1GPR35LTB4RCYSLTR2CYSLTR1 | |
| SCHEMBL30544 | 0.77 | GPR35 (0.55) | ALDH1A1GPR35LTB4RCYSLTR2CYSLTR1 | |
| SCHEMBL13098077 | 0.77 | KMT2A (0.53) | ALDH1A1GAAHPGDGPR35LTB4R | |
| SCHEMBL30412970 | 0.77 | GPR35 (0.45) | MAPK1GPR35LTB4RCYSLTR2CYSLTR1 | |
| SCHEMBL15286612 | 0.76 | GPR35 (0.43) | ALDH1A1GPR35LTB4RCYSLTR2CYSLTR1 | |
| SCHEMBL15286375 | 0.76 | GPR35 (0.43) | ALDH1A1GPR35LTB4RCYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577683-A1 | METHOD OF PREPARING 3-SUBSTITUTED THIOPHENE | NESTE OY (FI) | 1994-01-12 | — | — | EP | disclosed |
| WO-1992017465-A1 | METHOD OF PREPARING 3-SUBSTITUTED THIOPHENE | NESTE OY (FI) | 1992-10-15 | — | — | WO | disclosed |