Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.43 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30412970 | 0.98 | GPR35 (0.45) | GPR35CYSLTR2CYSLTR1BIDMCL1 | |
| SCHEMBL15286612 | 0.98 | GPR35 (0.43) | GPR35CYSLTR2CYSLTR1BIDMCL1 | |
| SCHEMBL4045273 | 0.93 | PKM (0.41) | GPR35CYSLTR2CYSLTR1LTB4RPKM | |
| SCHEMBL3077087 | 0.86 | PKM (0.43) | PKMMEN1MAPK1KMT2A | |
| SCHEMBL17353545 | 0.85 | GPR35 (0.57) | GPR35CYSLTR2CYSLTR1BIDMCL1 | |
| SCHEMBL4436638 | 0.85 | GPR35 (0.57) | GPR35CYSLTR2CYSLTR1BIDMCL1 | |
| SCHEMBL8516407 | 0.85 | GPR35 (0.57) | GPR35CYSLTR2CYSLTR1BIDMCL1 | |
| SCHEMBL7474906 | 0.85 | GPR35 (0.57) | GPR35CYSLTR2CYSLTR1BIDMCL1 | |
| SCHEMBL586816 | 0.84 | LIPG (0.40) | GPR35CYSLTR2CYSLTR1LIPGMEN1 | |
| SCHEMBL979606 | 0.84 | LIPG (0.40) | GPR35CYSLTR2CYSLTR1LIPGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | claimed |