Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3061994 | 0.85 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3ADRA2BADRA2C | |
| SCHEMBL3203375 | 0.82 | AOC3 (0.48) | SLC6A2SLC6A4SLC6A3ADRA2BADRA2C | |
| SCHEMBL6267693 | 0.81 | CARM1 (0.52) | SLC6A2SLC6A4SLC6A3ADRA2BADRA2C | |
| SCHEMBL16327199 | 0.79 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3ADRA2BADRA2C | |
| SCHEMBL15146911 | 0.79 | ADRA2B (0.57) | SLC6A2SLC6A4SLC6A3ADRA2BADRA2C | |
| SCHEMBL1088447 | 0.79 | ADRA2B (0.57) | SLC6A2SLC6A4SLC6A3ADRA2BADRA2C | |
| SCHEMBL27704211 | 0.78 | TSHR (0.46) | SLC6A2SLC6A4SLC6A3ADRA2BADRA2C | |
| SCHEMBL15003030 | 0.78 | ADRA2B (0.71) | SLC6A2SLC6A4SLC6A3ADRA2BADRA2C | |
| SCHEMBL22679007 | 0.77 | ADRA2B (0.50) | SLC6A2SLC6A4SLC6A3ADRA2BADRA2C | |
| SCHEMBL11322173 | 0.77 | TSHR (0.48) | SLC6A2SLC6A4SLC6A3ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154934-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND THEIR USE IN TREATING NEURODEGENERATIVE DISEASES | Université de Lille 2 Droit et Santé (FR) | 2017-04-19 | — | — | EP | disclosed |
| WO-2015193255-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND THEIR USE IN TREATING NEURODEGENERATIVE DISEASES | UNIVERSITE DE LILLE 2 DROIT ET SANTE (FR) | 2015-12-23 | — | — | WO | disclosed |
| EP-0402266-B1 | N-substituted lauramides, their preparation and compositions containing them | SANOFI ELF (FR) | 1994-02-02 | — | — | EP | disclosed |
| EP-0402266-A2 | N-substituted lauramides, their preparation and compositions containing them | ELF SANOFI (FR) | 1990-12-12 | — | — | EP | disclosed |