Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.58 |
| ▸ | CTSB | P07858 | 3/20 | 0.58 |
| ▸ | IL1RN | P18510 | 4/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.51 |
| ▸ | CTSD | P07339 | 8/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322444 | 0.94 | CTSK (0.62) | CTSKCTSBIL1RNERAP2ERAP1 | |
| SCHEMBL9322453 | 0.94 | CTSK (0.62) | CTSKCTSBIL1RNERAP2ERAP1 | |
| SCHEMBL9320607 | 0.86 | CTSK (0.55) | CTSKCTSBCTSD | |
| Trifluoroacetic Acid SCHEMBL7377191 | 0.82 | CTSK (0.58) | CTSKCTSBERAP2ERAP1CTSD | |
| SCHEMBL28526066 | 0.78 | CTSK (0.69) | CTSKCTSBCTSD | |
| SCHEMBL28526065 | 0.78 | CTSK (0.69) | CTSKCTSBCTSD | |
| SCHEMBL24049786 | 0.78 | CTSK (0.71) | CTSKCTSBCTSD | |
| SCHEMBL26269169 | 0.78 | CTSK (0.71) | CTSKCTSBCTSD | |
| SCHEMBL8651650 | 0.78 | CTSK (0.71) | CTSKCTSBCTSD | |
| Trifluoroacetic Acid SCHEMBL10443782 | 0.76 | CTSK (0.54) | CTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5359138-A | Endopeptidase inhibitors for treatment of amnesia and autoimmune diseases | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1994-10-25 | — | — | US | disclosed |