Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 13/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320600 | 0.92 | SLC6A2 (0.60) | SLC6A2SLC6A3SLC6A4TSHRMAPT | |
| SCHEMBL9321556 | 0.91 | SLC6A2 (0.56) | SLC6A2SLC6A3SLC6A4LMNAALDH1A1 | |
| SCHEMBL9322364 | 0.90 | SIGMAR1 (0.54) | SLC6A2SLC6A3SLC6A4LMNACNR1 | |
| SCHEMBL9320703 | 0.86 | SLC6A2 (0.53) | SLC6A2SLC6A4LMNAALDH1A1 | |
| SCHEMBL9320678 | 0.85 | SIGMAR1 (0.53) | SLC6A2SLC6A3SLC6A4LMNACNR1 | |
| SCHEMBL9320747 | 0.84 | SLC6A2 (0.62) | SLC6A2SLC6A3SLC6A4ALDH1A1 | |
| SCHEMBL9320630 | 0.83 | SLC6A2 (0.64) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL9321165 | 0.82 | SLC6A2 (0.70) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL9321455 | 0.82 | SLC6A2 (0.50) | SLC6A2SLC6A3SLC6A4LMNAMEN1 | |
| SCHEMBL9321494 | 0.80 | SLC6A2 (0.60) | SLC6A2SLC6A4ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310268-B1 | Substituted cycloalkanols | AMERICAN HOME PROD (US) | 1994-02-02 | — | — | EP | claimed |
| US-4826844-A | ANTIDEPRESSANT, ANXIOLYTIC AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-05-02 | — | — | US | claimed |
| EP-0310268-B1 | Substituted cycloalkanols | AMERICAN HOME PROD (US) | 1994-02-02 | — | — | EP | disclosed |
| US-4826844-A | ANTIDEPRESSANT, ANXIOLYTIC AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |