Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 12/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321455 | 0.89 | SLC6A2 (0.50) | SLC6A2LMNASLC6A4 | |
| SCHEMBL9321556 | 0.89 | SLC6A2 (0.56) | SLC6A2LMNAKDM4EALDH1A1SLC6A4 | |
| SCHEMBL9320636 | 0.86 | SLC6A2 (0.51) | SLC6A2LMNAALDH1A1SLC6A4 | |
| SCHEMBL9322364 | 0.86 | SIGMAR1 (0.54) | SLC6A2LMNASLC6A4 | |
| SCHEMBL9320678 | 0.81 | SIGMAR1 (0.53) | SLC6A2LMNASLC6A4 | |
| SCHEMBL9321494 | 0.80 | SLC6A2 (0.60) | SLC6A2HTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9320630 | 0.79 | SLC6A2 (0.64) | SLC6A2SLC6A4 | |
| SCHEMBL9320600 | 0.78 | SLC6A2 (0.60) | SLC6A2SLC6A4 | |
| SCHEMBL9320862 | 0.78 | SLC6A2 (0.51) | SLC6A2LMNAALDH1A1SLC6A4 | |
| SCHEMBL4367129 | 0.77 | SLC6A2 (0.71) | SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310268-B1 | Substituted cycloalkanols | AMERICAN HOME PROD (US) | 1994-02-02 | — | — | EP | claimed |
| US-4826844-A | ANTIDEPRESSANT, ANXIOLYTIC AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-05-02 | — | — | US | claimed |
| EP-0310268-A2 | Substituted cycloalkanols | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-04-05 | — | — | EP | claimed |
| US-4826844-A | ANTIDEPRESSANT, ANXIOLYTIC AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0310268-A2 | Substituted cycloalkanols | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-04-05 | — | — | EP | disclosed |