Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321148 | 0.94 | LMNA (0.47) | LMNAMAPK1HTTSMN1; SMN2S1PR2 | |
| SCHEMBL9320943 | 0.83 | S1PR2 (0.50) | LMNASMN1; SMN2S1PR2S1PR1S1PR3 | |
| SCHEMBL9321154 | 0.83 | EPHX2 (0.44) | S1PR2S1PR1S1PR3LPAR2 | |
| Ammonia Solution, Strong SCHEMBL30256649 | 0.81 | S1PR3 (0.54) | S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL9323056 | 0.79 | L3MBTL1 (0.61) | S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL9321681 | 0.79 | L3MBTL1 (0.61) | S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL9320964 | 0.79 | L3MBTL1 (0.61) | S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL9320267 | 0.79 | L3MBTL1 (0.61) | S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL9320260 | 0.79 | L3MBTL1 (0.61) | S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL9320218 | 0.79 | L3MBTL1 (0.61) | S1PR2S1PR1S1PR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282127-B1 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | PROCTER & GAMBLE (US) | 1994-02-02 | — | — | EP | disclosed |
| US-5099030-A | Phenols or phenolic ethers | THE PROCTER & GAMBLE COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-5045565-A | Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain | THE PROCTER & GAMBLE COMPANY (US) | 1991-09-03 | — | — | US | disclosed |
| EP-0282127-A2 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | THE PROCTER & GAMBLE COMPANY (US) | 1988-09-14 | — | — | EP | disclosed |