Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CNR1 | P21554 | 2/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.60 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 2/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321143 | 0.93 | CNR1 (0.73) | STSCNR1EPHX2CNR2TRPV1 | |
| SCHEMBL4134472 | 0.85 | STS (0.67) | STSLMNACNR1EPHX2CNR2 | |
| SCHEMBL23568294 | 0.84 | LMNA (0.56) | LMNA | |
| SCHEMBL3809498 | 0.83 | EPHX2 (0.84) | STSCNR1EPHX2CNR2TRPV1 | |
| SCHEMBL7329576 | 0.82 | STS (0.60) | STSLMNACNR1EPHX2CNR2 | |
| SCHEMBL12215285 | 0.82 | CNR1 (0.85) | STSCNR1EPHX2CNR2 | |
| SCHEMBL9320992 | 0.82 | TRPV1 (0.66) | CNR1EPHX2CNR2TRPV1 | |
| SCHEMBL24976638 | 0.82 | CA1 (0.55) | LMNA | |
| SCHEMBL9323087 | 0.81 | EPHX2 (0.78) | EPHX2TRPV1 | |
| SCHEMBL9321762 | 0.81 | EPHX2 (0.78) | EPHX2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282127-B1 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | PROCTER & GAMBLE (US) | 1994-02-02 | — | — | EP | disclosed |
| US-5099030-A | Phenols or phenolic ethers | THE PROCTER & GAMBLE COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-5045565-A | Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain | THE PROCTER & GAMBLE COMPANY (US) | 1991-09-03 | — | — | US | disclosed |
| EP-0282127-A2 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | THE PROCTER & GAMBLE COMPANY (US) | 1988-09-14 | — | — | EP | disclosed |