Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363619 | 0.86 | STS (0.61) | STSLMNACNR1EPHX2CNR2 | |
| SCHEMBL14287718 | 0.84 | LMNA (0.58) | LMNAALDH1A1 | |
| SCHEMBL9320928 | 0.82 | STS (0.66) | STSLMNACNR1EPHX2CNR2 | |
| SCHEMBL4134472 | 0.81 | STS (0.67) | STSLMNACNR1EPHX2CNR2 | |
| SCHEMBL14287721 | 0.79 | ACHE (0.52) | LMNA | |
| SCHEMBL16762031 | 0.79 | CNR1 (0.82) | STSCNR1EPHX2CNR2ALDH1A1 | |
| Nonivamide SCHEMBL3853816 | 0.79 | CYP1A2 (0.65) | CNR1CNR2HPGDALDH1A1TRPV1 | |
| SCHEMBL3809498 | 0.78 | EPHX2 (0.84) | STSCNR1EPHX2CNR2HPGD | |
| SCHEMBL12215285 | 0.78 | CNR1 (0.85) | STSCNR1EPHX2CNR2HPGD | |
| SCHEMBL7329573 | 0.78 | MCHR1 (0.56) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434365-A2 | HIV protease inhibitors useful for the treatment of aids | MERCK & CO. INC. (US) | 1991-06-26 | — | — | EP | claimed |