Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 12/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321425 | 0.94 | SLC2A1 (0.49) | SLC2A1ADRB2ADRB1LMNASLC6A2 | |
| SCHEMBL11018796 | 0.84 | ADRB2 (0.57) | SLC2A1ADRB2ADRB1LMNASLC6A2 | |
| SCHEMBL9764465 | 0.83 | ADRB2 (0.58) | SLC2A1ADRB2ADRB1LMNASLC6A2 | |
| SCHEMBL3982300 | 0.83 | ADRB2 (0.67) | SLC2A1ADRB2ADRB1SLC6A2SLC6A4 | |
| SCHEMBL9764380 | 0.83 | ADRB2 (0.53) | SLC2A1ADRB2ADRB1SLC6A2SLC6A4 | |
| SCHEMBL9764490 | 0.83 | ADRB2 (0.58) | SLC2A1ADRB2ADRB1LMNASLC6A2 | |
| SCHEMBL9764474 | 0.82 | ADRB2 (0.53) | SLC2A1ADRB2ADRB1SLC6A2SLC6A4 | |
| SCHEMBL9742101 | 0.82 | SLC2A1 (0.58) | SLC2A1ADRB2ADRB1LMNASLC6A2 | |
| SCHEMBL9741158 | 0.82 | SLC2A1 (0.58) | SLC2A1ADRB2ADRB1LMNASLC6A2 | |
| Hydrochloric Acid SCHEMBL9021318 | 0.82 | ADRB2 (0.61) | SLC2A1ADRB2ADRB1LMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401966-B1 | Phenethanolamine derivatives, processes for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LTD (GB) | 1994-01-19 | — | — | EP | claimed |
| US-5066678-A | PHENETHANDAMINE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | GLAXO GROUP LIMITED (GB) | 1991-11-19 | — | — | US | claimed |
| EP-0401966-A1 | Phenethanolamine derivatives, processes for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1990-12-12 | — | — | EP | claimed |
| EP-0401966-B1 | Phenethanolamine derivatives, processes for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LTD (GB) | 1994-01-19 | — | — | EP | disclosed |
| US-5066678-A | PHENETHANDAMINE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | GLAXO GROUP LIMITED (GB) | 1991-11-19 | — | — | US | disclosed |
| EP-0401966-A1 | Phenethanolamine derivatives, processes for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1990-12-12 | — | — | EP | disclosed |