Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6893840 | 1.00 | BACE1 (1.00) | BACE1KCNH2 | |
| SCHEMBL946113 | 0.81 | BACE1 (0.67) | BACE1KCNH2 | |
| SCHEMBL932233 | 0.79 | BACE1 (1.00) | BACE1KCNH2 | |
| SCHEMBL933023 | 0.79 | BACE1 (0.75) | BACE1KCNH2 | |
| SCHEMBL932149 | 0.78 | BACE1 (1.00) | BACE1KCNH2 | |
| SCHEMBL943489 | 0.74 | BACE1 (1.00) | BACE1KCNH2 | |
| SCHEMBL944390 | 0.74 | BACE1 (0.68) | BACE1KCNH2 | |
| SCHEMBL944524 | 0.74 | BACE1 (0.68) | BACE1KCNH2 | |
| SCHEMBL945358 | 0.74 | BACE1 (0.58) | BACE1KCNH2 | |
| SCHEMBL932101 | 0.74 | BACE1 (0.73) | BACE1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002408-A1 | NOVEL COMPOUNDS FOR TREATMENT OF NEURODEGENERATION ASSOCIATED WITH DISEASES, SUCH AS ALZHEIMER'S DISEASE OR DEMENTIA | ASTRAZENECA AB (SE) | 2011-01-06 | — | — | WO | disclosed |
| WO-2011002408-A1 | NOVEL COMPOUNDS FOR TREATMENT OF NEURODEGENERATION ASSOCIATED WITH DISEASES, SUCH AS ALZHEIMER'S DISEASE OR DEMENTIA | ASTRAZENECA AB (SE) | 2011-01-06 | — | — | WO | disclosed |