SCHEMBL9321982

SCHEMBL9321982

O=NN(Cc1ccccc1)S(=O)(=O)Cc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.49
CNR2 P34972 2/20 0.46
CA2 P00918 3/20 0.44
PRSS1 P07477 2/20 0.44
PRSS2 P07478 2/20 0.44
PRSS3 P35030 2/20 0.44
CA1 P00915 2/20 0.44
FAAH O00519 1/20 0.44
ELANE P08246 1/20 0.44
PRTN3 P24158 1/20 0.44
CA5A P35218 1/20 0.44
CA9 Q16790 1/20 0.44
USP2 O75604 1/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ESR1 P03372 1/20 0.41
F2 P00734 1/20 0.41
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
PTPN1 P18031 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2722528 0.84 CNR2 (0.49) HSP90AA1CNR2CA2PRSS1PRSS2
SCHEMBL1078094 0.80 HSP90AA1 (0.44) HSP90AA1CNR2CA2PRSS1PRSS2
SCHEMBL9321976 0.76 L3MBTL1 (0.43) CNR2CA2HPGDKMT2AMEN1
SCHEMBL3678710 0.76 CNR2 (0.60) CNR2CA9ALDH1A1LMNAHTT
SCHEMBL5576836 0.76 HSD17B10 (0.50) HSP90AA1CNR2CA2PRSS1PRSS2
SCHEMBL5966745 0.73 HSP90AA1 (0.52) HSP90AA1CNR2CA2PRSS1PRSS2
SCHEMBL8840586 0.70 HSP90AA1 (0.57) HSP90AA1CNR2CA2PRSS1PRSS2
SCHEMBL6503919 0.70 HSP90AA1 (0.57) HSP90AA1CNR2CA2PRSS1PRSS2
SCHEMBL27843526 0.70 PRSS1 (0.58) HSP90AA1CNR2CA2PRSS1PRSS2
SCHEMBL3174757 0.70 HSP90AA1 (0.57) HSP90AA1CNR2CA2PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0479156-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1994-01-12 EP disclosed
US-5252438-A For forming ultra hard negatives; nucleating development inhibitor hydrazines FUJI PHOTO FILM CO., LTD. (JP) 1993-10-12 US disclosed
EP-0479156-A1 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1992-04-08 EP disclosed