Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322205 | 1.00 | SIGMAR1 (0.47) | SIGMAR1MEN1KMT2ADPP7HRH3 | |
| SCHEMBL9321415 | 0.99 | SIGMAR1 (0.48) | SIGMAR1MEN1KMT2ADPP7HRH3 | |
| SCHEMBL9323630 | 0.92 | DPP7 (0.48) | SIGMAR1MEN1KMT2ADPP7 | |
| SCHEMBL9322164 | 0.91 | DPP7 (0.49) | SIGMAR1MEN1KMT2ADPP7 | |
| SCHEMBL9321345 | 0.89 | SIGMAR1 (0.51) | SIGMAR1HRH3CYP2D6SMAD3LTA4H | |
| SCHEMBL9323634 | 0.88 | SIGMAR1 (0.53) | SIGMAR1HRH3CYP2D6SMAD3LTA4H | |
| SCHEMBL9323726 | 0.84 | SIGMAR1 (0.56) | SIGMAR1HRH3CYP2D6SMAD3LTA4H | |
| SCHEMBL9323771 | 0.83 | SIGMAR1 (0.58) | SIGMAR1HRH3LTA4HHRH1 | |
| SCHEMBL9321403 | 0.82 | HRH3 (0.42) | SIGMAR1HRH3 | |
| SCHEMBL9322327 | 0.82 | HRH3 (0.42) | SIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235942-B1 | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-03-23 | — | — | EP | claimed |
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0235942-B1 | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| EP-0235942-A1 | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |