Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.91 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7228795 | 1.00 | MAPT (0.91) | MAPTHRH3POLBALDH1A1PKM | |
| SCHEMBL6738785 | 1.00 | MAPT (0.91) | MAPTHRH3POLBALDH1A1PKM | |
| SCHEMBL151720 | 0.98 | MAPT (0.95) | MAPTHRH3POLBALDH1A1PKM | |
| SCHEMBL7224479 | 0.98 | MAPT (0.95) | MAPTHRH3POLBALDH1A1PKM | |
| SCHEMBL9206204 | 0.98 | MAPT (0.95) | MAPTHRH3POLBALDH1A1PKM | |
| SCHEMBL151103 | 0.98 | MAPT (0.95) | MAPTHRH3POLBALDH1A1PKM | |
| SCHEMBL149979 | 0.96 | MAPT (1.00) | MAPTHRH3POLBALDH1A1PKM | |
| SCHEMBL154378 | 0.91 | MAPT (0.83) | MAPTHRH3POLBALDH1A1PKM | |
| SCHEMBL150332 | 0.91 | MAPT (0.83) | MAPTHRH3POLBALDH1A1PKM | |
| SCHEMBL28805019 | 0.91 | MAPT (0.91) | MAPTHRH3POLBALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |