Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1870772 | 0.79 | L3MBTL1 (0.52) | RAB9ANPC1MAPK1NFKB1NFKB2 | |
| SCHEMBL57185 | 0.72 | RAB9A (0.48) | RAB9ANPC1MAPK1NFKB1NFKB2 | |
| SCHEMBL4721991 | 0.72 | NPC1 (0.42) | RAB9ANPC1MAPK1NFKB1NFKB2 | |
| SCHEMBL6294638 | 0.70 | L3MBTL1 (0.59) | RAB9ANPC1MAPK1NFKB1NFKB2 | |
| SCHEMBL5909638 | 0.70 | MEN1 (0.44) | RAB9ANPC1MAPK1NFKB1NFKB2 | |
| SCHEMBL7720117 | 0.70 | NPC1 (0.41) | RAB9ANPC1MAPK1NFKB1NFKB2 | |
| SCHEMBL3652642 | 0.67 | NPC1 (1.00) | RAB9ANPC1MAPK1NFKB1NFKB2 | |
| SCHEMBL371042 | 0.67 | L3MBTL1 (0.74) | RAB9ANPC1MAPK1NFKB1NFKB2 | |
| SCHEMBL75848 | 0.65 | L3MBTL1 (0.70) | RAB9ANPC1MAPK1NFKB1NFKB2 | |
| SCHEMBL18212420 | 0.65 | L3MBTL1 (0.70) | RAB9ANPC1MAPK1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293651-B1 | Dicyanovinyl-substituted furan derivatives, process for their preparation, and their use | SUEDZUCKER AG (DE) | 1994-02-02 | — | — | EP | claimed |
| EP-0006536-B1 | PIPERIDINE-SPIRO-HYDANTOIN DERIVATIVES AND THEIR USE AS LIGHT STABILIZERS FOR SYNTHETIC POLYMERS | SANKYO COMPANY LIMITED (JP) | 1982-04-07 | — | — | EP | claimed |
| US-4219465-A | Piperidine-spiro-hydantoin derivatives and their use as polymer stabilizers | SANKYO COMPANY LIMITED (JP) | 1980-08-26 | — | — | US | claimed |
| EP-0006536-A1 | Piperidine-spiro-hydantoin derivatives and their use as light stabilizers for synthetic polymers | SANKYO COMPANY LIMITED (JP) | 1980-01-09 | — | — | EP | claimed |
| EP-0293651-B1 | Dicyanovinyl-substituted furan derivatives, process for their preparation, and their use | SUEDZUCKER AG (DE) | 1994-02-02 | — | — | EP | disclosed |
| US-5252757-A | Dicyanoazulenyl and dicyanovinyl substituted furan | SUDDEUTSCHE ZUCKER-AKTIENGSELLSCHAFT (DE) | 1993-10-12 | — | — | US | disclosed |
| US-5091538-A | DICYANOVINYLSUBSTITUTED FURAN DERIVATIVES | SUDDEUTSCHE ZUCKER-AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| EP-0293651-A2 | Dicyanovinyl-substituted furan derivatives, process for their preparation, and their use | SÜDZUCKER AKTIENGESELLSCHAFT MANNHEIM/OCHSENFURT (DE) | 1988-12-07 | — | — | EP | disclosed |
| EP-0006536-B1 | PIPERIDINE-SPIRO-HYDANTOIN DERIVATIVES AND THEIR USE AS LIGHT STABILIZERS FOR SYNTHETIC POLYMERS | SANKYO COMPANY LIMITED (JP) | 1982-04-07 | — | — | EP | disclosed |
| US-4219465-A | Piperidine-spiro-hydantoin derivatives and their use as polymer stabilizers | SANKYO COMPANY LIMITED (JP) | 1980-08-26 | — | — | US | disclosed |
| EP-0006536-A1 | Piperidine-spiro-hydantoin derivatives and their use as light stabilizers for synthetic polymers | SANKYO COMPANY LIMITED (JP) | 1980-01-09 | — | — | EP | disclosed |