Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995365 | 0.85 | HMGCR (0.41) | HMGCRPTPN7RECQLTDP1KDM4E | |
| SCHEMBL8766284 | 0.79 | PTPN7 (0.47) | HMGCRPTPN7RECQLTDP1KDM4E | |
| SCHEMBL31390449 | 0.78 | PTPN7 (0.50) | HMGCRPTPN7RECQLTDP1KDM4E | |
| SCHEMBL16594184 | 0.75 | HMGCR (0.47) | HMGCRPTPN7RECQLTDP1KDM4E | |
| SCHEMBL588384 | 0.73 | HMGCR (0.39) | HMGCRPTPN7RECQLTDP1KDM4E | |
| SCHEMBL3104220 | 0.73 | — | — | |
| SCHEMBL996455 | 0.73 | — | — | |
| SCHEMBL1088162 | 0.73 | — | — | |
| SCHEMBL1088314 | 0.72 | LMNA (0.44) | HMGCRPTPN7RECQLTDP1KDM4E | |
| SCHEMBL2972124 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409234-B1 | Alpha-hydroxyketone derivatives, liquid crystal compositions containing said derivatives, and liquid crystal devices using said compositions | CHISSO CORP (JP) | 1994-02-16 | — | — | EP | disclosed |
| US-5164112-A | Optical activity, ferroelectric, short response times | CHISSO CORPORATION (JP) | 1992-11-17 | — | — | US | disclosed |
| US-5055222-A | Enantiomorph for use in liquid crystal display elements | CHISSO CORPORATION (JP) | 1991-10-08 | — | — | US | disclosed |
| EP-0409234-A2 | Alpha-hydroxyketone derivatives, liquid crystal compositions containing said derivatives, and liquid crystal devices using said compositions | Chisso Corporation (JP) | 1991-01-23 | — | — | EP | disclosed |
| EP-0267758-A2 | Alpha-substituted-propionic acid esters | Chisso Corporation (JP) | 1988-05-18 | — | — | EP | disclosed |