SCHEMBL588384

SCHEMBL588384

CCCCC#CC(=O)CC(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 3/20 0.39
FFAR1 O14842 1/20 0.39
PTPN7 P35236 5/20 0.37
TDP1 Q9NUW8 3/20 0.35
ALDH1A1 P00352 2/20 0.35
RECQL P46063 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
ALOX12 P18054 1/20 0.35
BLM P54132 1/20 0.35
KMT2A Q03164 1/20 0.35
MCL1 Q07820 1/20 0.35
TSHR P16473 1/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2122845 0.79 ALDH1A1 (0.37) FFAR1TDP1ALDH1A1SMN1; SMN2CA2
SCHEMBL2122055 0.79 HMGCR (0.44) HMGCRPTPN7TDP1ALDH1A1RECQL
SCHEMBL12003514 0.77 HMGCR (0.47) HMGCRPTPN7TDP1ALDH1A1RECQL
SCHEMBL997133 0.77 HMGCR (0.47) HMGCRPTPN7TDP1ALDH1A1RECQL
SCHEMBL995365 0.75 HMGCR (0.41) HMGCRPTPN7TDP1ALDH1A1RECQL
SCHEMBL2123154 0.75 TDP1 (0.50) FFAR1TDP1ALDH1A1SMN1; SMN2TSHR
SCHEMBL9322780 0.73 HMGCR (0.40) HMGCRPTPN7TDP1ALDH1A1RECQL
SCHEMBL998012 0.73 HMGCR (0.40) HMGCRPTPN7TDP1ALDH1A1RECQL
SCHEMBL16594184 0.73 HMGCR (0.47) HMGCRPTPN7TDP1ALDH1A1RECQL
SCHEMBL995772 0.72 PTPN7 (0.50) HMGCRPTPN7TDP1ALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2442783-B1 NOVEL DEODORISING COMPOSITIONS AND DEODORISING PRODUCTS CONTAINING SAME ROBERTET SA (FR) 2017-08-09 EP claimed
US-9265852-B2 Deordorising compositions and deodorising products containing same ROBERTET S.A. (FR) 2016-02-23 US claimed
US-20120201778-A1 NOVEL DEORDORISING COMPOSITIONS AND DEODORISING PRODUCTS CONTAINING SAME ROBERTET S.A. (FR) 2012-08-09 US claimed
WO-2010146258-A2 NOVEL DEODORISING COMPOSITIONS AND DEODORISING PRODUCTS CONTAINING SAME ROBERTET S.A. (FR) 2010-12-23 WO claimed
CN-115322211-B Preparation method of alkenyl substituted-alpha-hydroxy borate compound 香港科技大学深圳研究院 2025-02-25 CN disclosed
EP-2442783-B1 NOVEL DEODORISING COMPOSITIONS AND DEODORISING PRODUCTS CONTAINING SAME ROBERTET SA (FR) 2017-08-09 EP disclosed
US-9265852-B2 Deordorising compositions and deodorising products containing same ROBERTET S.A. (FR) 2016-02-23 US disclosed
US-20120201778-A1 NOVEL DEORDORISING COMPOSITIONS AND DEODORISING PRODUCTS CONTAINING SAME ROBERTET S.A. (FR) 2012-08-09 US disclosed
EP-2442783-A2 NOVEL DEODORISING COMPOSITIONS AND DEODORISING PRODUCTS CONTAINING SAME Robertet S.A. (FR) 2012-04-25 EP disclosed
EP-1753746-B8 NOVEL PYRROLE DERIVATIVES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY ROTTAPHARM SPA (IT) 2012-02-15 EP disclosed
EP-1753746-B1 NOVEL PYRROLE DERIVATIVES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY ROTTAPHARM SPA (IT) 2011-07-27 EP disclosed
US-7906501-B2 Pyrrole derivatives with angiotensin II antagonist activity ROTTAPHARM S.P.A. (IT) 2011-03-15 US disclosed
WO-2010146258-A2 NOVEL DEODORISING COMPOSITIONS AND DEODORISING PRODUCTS CONTAINING SAME ROBERTET S.A. (FR) 2010-12-23 WO disclosed
US-20070244170-A1 Novel Pyrrole Derivatives with Angiotensin II Antagonist Activity ROTTAPHARM BIOTECH S.R.L. (IT) 2007-10-18 US disclosed
EP-1753746-A2 NOVEL PYRROLE DERIVATIVES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY ROTTAPHARM S.P.A. (IT) 2007-02-21 EP disclosed
WO-2005105789-A2 NOVEL PYRROLE DERIVATIVES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY ROTTAPHARM S.P.A. (IT) 2005-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070244170-A1 Novel Pyrrole Derivatives with Angiotensin II Antagonist Activity AGTR2, AGTR1, REN HMGCR 3305/4885FFAR1 757/4885PTPN7 1363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.