Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 8/20 | 0.61 |
| ▸ | ESR1 | P03372 | 5/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13760082 | 0.93 | ESR1 (0.53) | ESR2ESR1HSD11B1L3MBTL1ALOX5AP | |
| SCHEMBL9342028 | 0.88 | ESR2 (0.58) | ESR2ESR1HSD11B1ALDH1A1MMP2 | |
| SCHEMBL7189035 | 0.86 | ESR2 (0.80) | ESR2ESR1HSD11B1HSD17B10CYP3A4 | |
| SCHEMBL9320790 | 0.86 | ESR2 (0.74) | ESR2ESR1HSD11B1ALDH1A1L3MBTL1 | |
| SCHEMBL14451249 | 0.84 | ESR1 (0.44) | ESR2ESR1HSD11B1HSD17B10MAPT | |
| SCHEMBL25411522 | 0.82 | ESR2 (0.80) | ESR2ESR1HSD11B1ALDH1A1L3MBTL1 | |
| SCHEMBL545221 | 0.81 | ESR2 (0.63) | ESR2ESR1HSD11B1ALDH1A1MMP2 | |
| SCHEMBL870311 | 0.81 | ESR2 (0.90) | ESR2ESR1HSD11B1ALDH1A1L3MBTL1 | |
| SCHEMBL8411084 | 0.81 | ESR2 (0.90) | ESR2ESR1HSD11B1ALDH1A1L3MBTL1 | |
| SCHEMBL1414959 | 0.80 | OPRM1 (0.46) | HSD11B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 720 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346954-B1 | PREPARATION FOR PRODUCING A COVER LAYER FOR AN ELECTROLUMINESCENT SECURITY ELEMENT OF A SECURITY DOCUMENT AND/OR VALUE DOCUMENT | BUNDESDRUCKEREI GMBH (DE) | 2017-04-12 | — | — | EP | claimed |
| EP-2676803-B1 | Method for producing a polymer layer composite with multilayer personalization and/or individualisation | BUNDESDRUCKEREI GMBH (DE) | 2016-09-14 | — | — | EP | claimed |
| US-20160129679-A1 | METHOD FOR THE PRODUCTION OF A POLYCARBONATE LAMINATE | BUNDESDRUCKEREI GMBH (DE) | 2016-05-12 | — | — | US | claimed |
| US-8636862-B2 | Method for producing a polycarbonate layered composite | BUNDESDRUCKEREI GMBH (DE) | 2014-01-28 | — | — | US | claimed |
| EP-2676803-A1 | Method for producing a polymer layer composite with multilayer personalization and/or individualisation | Bundesdruckerei GmbH (DE) | 2013-12-25 | — | — | EP | claimed |
| EP-2205436-B1 | METHOD FOR PRODUCING A POLYCARBONATE LAYERED COMPOSITE | BUNDESDRUCKEREI GMBH (DE) | 2011-04-20 | — | — | EP | claimed |
| EP-2205437-B1 | METHOD FOR PRODUCING A POLYCARBONATE LAYERED COMPOSITE | BUNDESDRUCKEREI GMBH (DE) | 2011-04-13 | — | — | EP | claimed |
| EP-2205686-B1 | METHOD FOR THE PRODUCTION OF A POLYCARBONATE LAMINATE | BUNDESDRUCKEREI GMBH (DE) | 2011-03-16 | — | — | EP | claimed |
| US-20100310812-A1 | METHOD FOR PRODUCING A POLYCARBONATE LAYERED COMPOSITE | BUNDESDRUCKEREI GMBH (DE) | 2010-12-09 | — | — | US | claimed |
| JP-2009521548-A | — | — | 2009-06-04 | — | — | JP | claimed |
| US-20050049439-A1 | Method for making salts hydroxy-substituted hydrocarbons | GENERAL ELECTRIC COMPANY | 2005-03-03 | — | — | US | claimed |
| US-6849706-B1 | Copolyetherimides | GENERAL ELECTRIC COMPANY (US) | 2005-02-01 | — | — | US | claimed |
| EP-0999033-B1 | Process and apparatus for forming plastic sheet | ROHM & HAAS (US) | 2004-06-16 | — | — | EP | claimed |
| US-6706788-B2 | HEAT RESISTANCE, WELD LINE STRENGTH | BAYER AKTIENGESELLSCHAFT (DE) | 2004-03-16 | — | — | US | claimed |
| US-6472031-B1 | POLYCARBONATE SHEET HAVING LOW RESIDUAL STRESS AND HIGH SURFACE QUALITY; OPTICAL WINDOWS, OPTICAL FILTERS, RECORDING MEDIA, AND LIQUID CRYSTAL DISPLAYS; | ROHM AND HAAS COMPANY | 2002-10-29 | — | — | US | claimed |
| US-6337371-B2 | MIXTURE | TECHNO POLYMER CO., LTD. (JP) | 2002-01-08 | — | — | US | claimed |
| US-6280808-B1 | Process and apparatus for forming plastic sheet | ROHM AND HAAS COMPANY | 2001-08-28 | — | — | US | claimed |
| US-6262173-B1 | HAVING IMPACT RESISTANCE, HEAT RESISTANCE, CHEMICAL RESISTANCE AND WEATHER RESISTANCE | TECHNO POLYMER CO., LTD. (JP) | 2001-07-17 | — | — | US | claimed |
| US-6183829-B1 | Process and apparatus for forming plastic sheet | ROHM AND HAAS COMPANY | 2001-02-06 | — | — | US | claimed |
| EP-0999033-A2 | Process and apparatus for forming plastic sheet | ROHM AND HAAS COMPANY (US) | 2000-05-10 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049439-A1 | Method for making salts hydroxy-substituted hydrocarbons | HDHD5, SHH, HAAO | ESR2 3768/4885ESR1 2614/4885HSD11B1 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.