Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 18/20 | 0.71 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.59 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29780388 | 0.86 | VCAM1 (0.73) | VCAM1NPBWR1MCHR1ALDH1A1 | |
| SCHEMBL10452716 | 0.86 | VCAM1 (0.73) | VCAM1NPBWR1MCHR1ALDH1A1 | |
| SCHEMBL809482 | 0.86 | VCAM1 (0.73) | VCAM1NPBWR1MCHR1ALDH1A1 | |
| SCHEMBL376610 | 0.85 | VCAM1 (0.71) | VCAM1NPBWR1MCHR1ALDH1A1 | |
| SCHEMBL30430066 | 0.85 | VCAM1 (0.71) | VCAM1NPBWR1MCHR1ALDH1A1 | |
| SCHEMBL1184879 | 0.83 | VCAM1 (1.00) | VCAM1NPBWR1MCHR1ALDH1A1 | |
| SCHEMBL1097803 | 0.83 | VCAM1 (0.69) | VCAM1NPBWR1MCHR1ALDH1A1 | |
| SCHEMBL332971 | 0.83 | VCAM1 (0.69) | VCAM1NPBWR1MCHR1ALDH1A1 | |
| Potassium Ion SCHEMBL9585856 | 0.83 | VCAM1 (0.69) | VCAM1NPBWR1MCHR1ALDH1A1 | |
| SCHEMBL176738 | 0.83 | VCAM1 (0.69) | VCAM1NPBWR1MCHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605310-B | Synthesis method of aza five-membered ring and three-membered ring carboxylic ester derivative and salt thereof | 都创(上海)医药科技股份有限公司 | 2024-05-07 | — | — | CN | claimed |
| EP-0240366-B1 | Perhydrothiazepine and perhydroazepine derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1994-01-26 | — | — | EP | disclosed |
| EP-0220865-B1 | LACTAM DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HYPOTENSIVE AGENTS | SANKYO COMPANY LIMITED (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4778790-A | HYPOTENSIVE AGENTS | SANKYO COMPANY LIMITED (JP) | 1988-10-18 | — | — | US | disclosed |
| US-4734410-A | Lactam derivatives and their use as hypotensive agents | SANKYO COMPANY LIMITED (JP) | 1988-03-29 | — | — | US | disclosed |
| EP-0240366-A2 | Perhydrothiazepine and perhydroazepine derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |
| EP-0220865-A2 | Lactam derivatives, their preparation and their use as hypotensive agents | SANKYO COMPANY LIMITED (JP) | 1987-05-06 | — | — | EP | disclosed |