SCHEMBL376610

SCHEMBL376610

O=[N+]([O-])c1cc(S(=O)(=O)Cl)ccc1Cl

nearest known ligand 0.71

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 18/20 0.71
NPBWR1 P48145 1/20 0.59
MCHR1 Q99705 1/20 0.59
ALDH1A1 P00352 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30430066 1.00 VCAM1 (0.71) VCAM1NPBWR1MCHR1ALDH1A1
Methyl Alcohol SCHEMBL29280927 0.95 VCAM1 (0.65) VCAM1NPBWR1MCHR1ALDH1A1
SCHEMBL7721899 0.90 VCAM1 (0.59) VCAM1NPBWR1MCHR1ALDH1A1
SCHEMBL10452716 0.86 VCAM1 (0.73) VCAM1NPBWR1MCHR1ALDH1A1
SCHEMBL29780388 0.86 VCAM1 (0.73) VCAM1NPBWR1MCHR1ALDH1A1
SCHEMBL809482 0.86 VCAM1 (0.73) VCAM1NPBWR1MCHR1ALDH1A1
SCHEMBL8675051 0.86 VCAM1 (0.55) VCAM1NPBWR1MCHR1ALDH1A1
SCHEMBL9323485 0.85 VCAM1 (0.71) VCAM1NPBWR1MCHR1ALDH1A1
SCHEMBL5925285 0.85 MMP1 (0.65) VCAM1NPBWR1MCHR1
SCHEMBL3813276 0.84 VCAM1 (0.50) VCAM1NPBWR1MCHR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 816 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119425423-A Positively charged composite membrane and preparation method and application thereof 中国石油化工股份有限公司 2025-02-14 CN claimed
CN-119143705-A Benzofuran lymph specific tyrosine phosphatase inhibitor and preparation method and application thereof 山东大学 2024-12-17 CN claimed
CN-117820417-A Near-infrared bimodal optical probe and preparation method and application thereof 中国药科大学 2024-04-05 CN claimed
CN-115710251-A Myeloid differentiation factor 88 inhibitor and preparation method and application thereof 杭州医学院 2023-02-24 CN claimed
CN-109694338-B Methoxy acetophenone derivative and preparation method and application thereof 河南科技大学 2021-09-24 CN claimed
CN-109516987-B Preparation method of avibactam intermediate 江西富祥药业股份有限公司 2020-07-24 CN claimed
CN-106568857-B A method of the related substance of measurement palm pipotiazine 岳阳新华达制药有限公司 2019-08-06 CN claimed
CN-105669502-A Chromogenic substrate of 3-nitro-4-chlorine-benzenesulfonamide glutathione-S-transsulfurase 重庆医科大学 2016-06-15 CN claimed
CN-1267414-C Separating purification of 3-nitro-4-chlorofenizon SHANGHAI APPLIED TECHNOLOGY CO (CN) 2006-08-02 CN claimed
CN-1680309-A Separating purification of 3-nitro-4-chlorofenizon SHANGHAI APPLIED TECHNOLOGY CO (CN) 2005-10-12 CN claimed
EP-0248334-B1 PROCESS FOR THE MANUFACTURE OF 2-NITRO-4-SULFAMYL-DIPHENYL AMINE DYES HOECHST AKTIENGESELLSCHAFT (DE) 1993-01-13 EP claimed
US-4851575-A Process for the preparation of 2-nitro-4-sulfamyldiphenylamine dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1989-07-25 US claimed
EP-0289847-A1 Preparation of 2-Chloro-5-nitro- and 4-Chloro-3-nitrobenzene-sulfonyl chloride BAYER AG (DE) 1988-11-09 EP claimed
JP-6329618-A None JP disclosed
CN-122071469-A PARG inhibitor and preparation method and application thereof 烟台新药创制山东省实验室 2026-05-22 CN disclosed
US-20260049088-A1 TRICYCLIC HETEROCYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF DANATLAS PHARMACEUTICALS CO LTD (CN) 2026-02-19 US disclosed
US-3954476-A Diffusable dye-releasing compounds which are cleavable upon oxidation EASTMAN KODAK COMPANY (US) 1976-05-04 US disclosed
US-3945992-A DISAZO DYES FOR POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-03-23 US disclosed
US-3945991-A Heterocyclic azo compounds containing a quaternated hydrazide group CIBA-GEIGY AG (CH) 1976-03-23 US disclosed
US-3932380-A DIFFUSION TRANSFER COLOR PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049088-A1 TRICYCLIC HETEROCYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF SRD5A2, CBR1, SRD5A1 VCAM1 4636/4885NPBWR1 360/4885MCHR1 257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.