Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322337 | 0.95 | KCNA3 (0.43) | KCNA3GBA1SIGMAR1SPHK1HRH3 | |
| SCHEMBL9322204 | 0.90 | SPHK1 (0.46) | KCNA3SPHK1 | |
| SCHEMBL9322512 | 0.88 | HRH3 (0.40) | KCNA3GBA1HRH3 | |
| SCHEMBL9322325 | 0.86 | KCNA3 (0.41) | KCNA3GBA1SPHK1HRH3 | |
| SCHEMBL9324674 | 0.83 | HRH3 (0.38) | SIGMAR1HRH3 | |
| SCHEMBL11932479 | 0.82 | GBA1 (0.49) | KCNA3GBA1SIGMAR1SPHK1HRH3 | |
| SCHEMBL9322145 | 0.81 | HRH3 (0.41) | HRH3 | |
| SCHEMBL9322161 | 0.81 | HRH3 (0.41) | HRH3 | |
| SCHEMBL9322241 | 0.78 | HRH3 (0.45) | SIGMAR1HRH3 | |
| SCHEMBL10771016 | 0.78 | HRH3 (0.39) | SIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |