Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9323544 | 0.95 | KCNA3 (0.40) | KCNA3SPHK1GBA1SIGMAR1HRH3 | |
| SCHEMBL9322512 | 0.92 | HRH3 (0.40) | KCNA3GBA1HRH3HRH2HRH1 | |
| SCHEMBL9322204 | 0.92 | SPHK1 (0.46) | KCNA3SPHK1 | |
| SCHEMBL9322325 | 0.90 | KCNA3 (0.41) | KCNA3SPHK1GBA1HRH3CCR5 | |
| SCHEMBL11932479 | 0.83 | GBA1 (0.49) | KCNA3SPHK1GBA1SIGMAR1HRH3 | |
| SCHEMBL9321324 | 0.81 | SMN1; SMN2 (0.47) | HRH3 | |
| SCHEMBL9322277 | 0.80 | SIGMAR1 (0.44) | SIGMAR1HRH3 | |
| SCHEMBL9322345 | 0.80 | HRH3 (0.45) | HRH3HRH1 | |
| SCHEMBL9323743 | 0.79 | THRA (0.40) | — | |
| SCHEMBL6957321 | 0.79 | KCNA3 (0.53) | KCNA3SPHK1GBA1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1038062-A | — | — | None | — | — | JP | disclosed |
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |