SCHEMBL9323604

SCHEMBL9323604

O=C(Cl)c1cc2cc(O)ccc2cc1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.54
POLA1 P09884 1/20 0.52
ESR1 P03372 4/20 0.45
ESR2 Q92731 4/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
PKM P14618 1/20 0.45
CES2 O00748 1/20 0.45
TDP1 Q9NUW8 2/20 0.44
MITF O75030 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
NCOA1 Q15788 1/20 0.44
NCOA3 Q9Y6Q9 1/20 0.44
ALDH1A1 P00352 2/20 0.44
TSHR P16473 2/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3924507 0.83 LCK (0.52) SRCPOLA1MEN1KMT2ACES2
SCHEMBL216334 0.82 CA12 (0.61) SRCPOLA1MEN1KMT2ACES2
SCHEMBL124773 0.82 CA12 (0.61) SRCPOLA1MEN1KMT2ACES2
SCHEMBL11214665 0.82 MAPT (0.59) MEN1KMT2ATDP1MITFGAA
SCHEMBL29434908 0.82 CA12 (0.61) SRCPOLA1MEN1KMT2ACES2
SCHEMBL1889553 0.82 MEN1 (0.63) MEN1KMT2ATDP1MITFGAA
SCHEMBL12953085 0.81 SRC (0.54) SRCPOLA1ESR1ESR2MEN1
SCHEMBL8906715 0.79 CES2 (0.70) ESR1ESR2MEN1KMT2APKM
SCHEMBL8668036 0.79 NPC1 (0.54) POLA1MEN1KMT2AMAPTALDH1A1
SCHEMBL14880308 0.78 SRC (0.63) SRCPOLA1MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0295737-B1 Branched polycarbonates containing hydroxy-naphthoic acids or their derivatives, and process for preparing them ENICHEM SPA (IT) 1994-02-09 EP claimed
US-4920198-A Branched polycarbonate from hydroxy-naphthoic acid or derivative, and process for preparing ENICHEM TECNORESINE S.P.A. (IT) 1990-04-24 US claimed
EP-0295737-A2 Branched polycarbonates containing hydroxy-naphthoic acids or their derivatives, and process for preparing them ENICHEM S.p.A. (IT) 1988-12-21 EP claimed
EP-0295737-B1 Branched polycarbonates containing hydroxy-naphthoic acids or their derivatives, and process for preparing them ENICHEM SPA (IT) 1994-02-09 EP disclosed
US-4920198-A Branched polycarbonate from hydroxy-naphthoic acid or derivative, and process for preparing ENICHEM TECNORESINE S.P.A. (IT) 1990-04-24 US disclosed
EP-0295737-A2 Branched polycarbonates containing hydroxy-naphthoic acids or their derivatives, and process for preparing them ENICHEM S.p.A. (IT) 1988-12-21 EP disclosed