SCHEMBL1889553

SCHEMBL1889553

O=C(Cl)c1cc2ccccc2cc1O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.63
KMT2A Q03164 6/20 0.63
MAPT P10636 4/20 0.63
GAA P10253 2/20 0.63
MITF O75030 1/20 0.63
NCOA1 Q15788 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
NCOA3 Q9Y6Q9 1/20 0.63
KDM4E B2RXH2 3/20 0.51
ALDH1A1 P00352 1/20 0.51
CASP1 P29466 1/20 0.51
CASP7 P55210 1/20 0.51
NPC1 O15118 7/20 0.49
RAB9A P51151 6/20 0.49
POLB P06746 3/20 0.49
MAPK1 P28482 1/20 0.47
LMNA P02545 1/20 0.46
NPY1R P25929 1/20 0.46
HTT P42858 1/20 0.46
NPY2R P49146 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11214665 0.96 MAPT (0.59) MEN1KMT2AMAPTGAAMITF
SCHEMBL29752028 0.86 ALDH1A1 (0.50) MEN1KMT2AMAPTGAAMITF
SCHEMBL1958554 0.86 ALDH1A1 (0.50) MEN1KMT2AMAPTGAAMITF
SCHEMBL9323604 0.82 SRC (0.54) MEN1KMT2AMAPTGAAMITF
SCHEMBL9324678 0.80 GRIN2D (0.71) MEN1KMT2AMAPTGAAMITF
SCHEMBL3924507 0.80 LCK (0.52) MEN1KMT2AMAPTGAAMITF
SCHEMBL6460 0.80 GRIN2D (0.66) MEN1KMT2AMAPTGAAMITF
SCHEMBL27593821 0.80 MEN1 (0.60) MEN1KMT2AMAPTGAAMITF
SCHEMBL29358330 0.80 GRIN2D (0.66) MEN1KMT2AMAPTGAAMITF
SCHEMBL9017415 0.78 GRIN2D (0.63) MEN1KMT2AMAPTGAAMITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118026974-A Chromonol containing difuran diamine structure and disazo pigment derived from same 江苏丽王科技有限公司 2024-05-14 CN claimed
CN-111039812-B Method for preparing naphthol AS-OL by micro-channel continuous method 泰安岳海新材料股份有限公司 2023-01-06 CN claimed
CN-111039812-A Method for preparing naphthol AS-OL by micro-channel continuous method 肥城岳海化工有限公司 2020-04-21 CN claimed
US-7531691-B2 Method for producing naphthalene carboxylic acid amide compound UENO FINE CHEMICALS INDUSTRY, LTD. (JP) 2009-05-12 US claimed
CN-100374414-C Naphthurea composition for preparation of carrier generation materials and process for preparing same UNIV TIANJIN (CN) 2008-03-12 CN claimed
US-20080045720-A1 Method for producing naphthalene carboxylic acid amide compound UENO FINE CHEMICALS INDUSTRY, LTD. (JP) 2008-02-21 US claimed
EP-1867629-A2 Method for producing naphthalene carboxylic acid amide compound Ueno Fine Chemicals Industry, Ltd. (JP) 2007-12-19 EP claimed
CN-101088987-A Method for producing naphthalene carboxylic acid amide compound UENO FINE CHEMICAL IND (JP) 2007-12-19 CN claimed
CN-1827595-A Naphthurea composition for preparation of carrier generation materials and process for preparing same UNIV TIANJIN (CN) 2006-09-06 CN claimed
EP-0712848-B1 Process of preparation of 3-hydroxy-N-benzimidazolon-5-yl-naphth-2-amides, in high purity for the preparation of azodyes CLARIANT GMBH (DE) 2000-09-27 EP claimed
US-5756757-A Process for the preparation of 3-hydroxy-N-benzimidazolon-5-yl-2-naphthamide in the high purity required of azo pigments HOECHST AKTIENGESELLSCHAFT (DE) 1998-05-26 US claimed
JP-58210055-A None JP disclosed
JP-59204160-A None JP disclosed
JP-58201755-A None JP disclosed
JP-63021645-A None JP disclosed
JP-S58201755-A NOVEL 2-HYDROXY-3-NAPHTHOIC ACID ANILIDE COMPOUND RICOH CO LTD 1983-11-24 JP disclosed
US-4207110-A 2,5-DIALKOXY-4-MORPHOLINO-BENZENE DIAZONIUM SALT AND COUPLER COMBINATION TO GIVE BLACK IMAGE HOECHST AKTIENGESELLSCHAFT (DE) 1980-06-10 US disclosed
US-4054456-A Diazo photographic materials containing 2-hydroxy 3-naphthanilide coupler FUJI PHOTO FILM CO., LTD. (JA) 1977-10-18 US disclosed
US-4042704-A FERTILITY CONTROL AGENTS SANDOZ, INC. (US) 1977-08-16 US disclosed
US-3985725-A Quinolino-azo-aceto-acetylaminobenzimidazolone pigments fast to heat HOECHST AKTIENGESELLSCHAFT (DT) 1976-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080045720-A1 Method for producing naphthalene carboxylic acid amide compound NAAA, AADAC, NAT1 MEN1 3096/4885KMT2A 678/4885MAPT 1876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.