SCHEMBL9323640

SCHEMBL9323640

CCCCOC(C)C(=O)C(C)OCCCC

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
ATM Q13315 1/20 0.41
TSHR P16473 4/20 0.39
HPGD P15428 1/20 0.39
DNM1 Q05193 1/20 0.39
LMNA P02545 4/20 0.38
CYP1A2 P05177 2/20 0.37
CYP2C19 P33261 2/20 0.37
ESR1 P03372 1/20 0.37
CYP2D6 P10635 1/20 0.37
MAPK1 P28482 1/20 0.37
NR1H2 P55055 1/20 0.37
RNASEL Q05823 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HCAR2 Q8TDS4 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
PDE4D Q08499 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9323316 0.93 DNM1 (0.47) TSHRDNM1LMNATP53
SCHEMBL9322459 0.91 DNM1 (0.50) TSHRDNM1LMNA
SCHEMBL442956 0.84 ALDH1A1 (0.43) ALDH1A1ATMTSHRMAPK1HCAR2
SCHEMBL9628641 0.84 ALDH1A1 (0.43) ALDH1A1ATMTSHRHPGDDNM1
SCHEMBL16968096 0.84 ALDH1A1 (0.48) ALDH1A1ATMTSHRHPGDDNM1
SCHEMBL9318736 0.84 ALDH1A1 (0.43) ALDH1A1ATMTSHRMAPK1HCAR2
SCHEMBL7673548 0.84 CA1 (0.43) ALDH1A1ATMTSHRHPGDDNM1
SCHEMBL9318505 0.84 ALDH1A1 (0.43) ALDH1A1ATMTSHRMAPK1HCAR2
SCHEMBL13715542 0.82 ALDH1A1 (0.52) ALDH1A1ATMTSHRHPGDLMNA
Hydrochloric Acid SCHEMBL9687274 0.82 ALDH1A1 (0.41) ALDH1A1ATMTSHRDNM1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0409234-B1 Alpha-hydroxyketone derivatives, liquid crystal compositions containing said derivatives, and liquid crystal devices using said compositions CHISSO CORP (JP) 1994-02-16 EP disclosed
US-5164112-A Optical activity, ferroelectric, short response times CHISSO CORPORATION (JP) 1992-11-17 US disclosed
EP-0409234-A2 Alpha-hydroxyketone derivatives, liquid crystal compositions containing said derivatives, and liquid crystal devices using said compositions Chisso Corporation (JP) 1991-01-23 EP disclosed