Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ASAH2 | Q9NR71 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1503531 | 0.81 | PKM (0.56) | CTNNB1MAPK1POLBL3MBTL1ALDH1A1 | |
| SCHEMBL7186388 | 0.81 | L3MBTL1 (0.62) | CTNNB1MAPTNPSR1LMNAPOLB | |
| SCHEMBL8421294 | 0.80 | PARP10 (0.59) | CTNNB1MAPTALDH1A1 | |
| SCHEMBL1503528 | 0.80 | MAPT (0.69) | CTNNB1MAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL12691656 | 0.80 | CTNNB1 (0.52) | CTNNB1MAPTL3MBTL1GAAPLK1 | |
| SCHEMBL9323736 | 0.79 | MAPT (0.41) | MAPTMAPK1NPSR1LMNAPOLB | |
| SCHEMBL19337421 | 0.78 | CTNNB1 (0.57) | CTNNB1MAPTL3MBTL1GAAPLK1 | |
| SCHEMBL18417687 | 0.78 | MAPT (0.49) | CTNNB1MAPTMAPK1ASAH2LMNA | |
| SCHEMBL1302689 | 0.78 | GAA (0.56) | MAPTMAPK1NPSR1LMNAPOLB | |
| SCHEMBL29404503 | 0.78 | GAA (0.56) | MAPTMAPK1NPSR1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409234-B1 | Alpha-hydroxyketone derivatives, liquid crystal compositions containing said derivatives, and liquid crystal devices using said compositions | CHISSO CORP (JP) | 1994-02-16 | — | — | EP | disclosed |
| US-5164112-A | Optical activity, ferroelectric, short response times | CHISSO CORPORATION (JP) | 1992-11-17 | — | — | US | disclosed |
| EP-0409234-A2 | Alpha-hydroxyketone derivatives, liquid crystal compositions containing said derivatives, and liquid crystal devices using said compositions | Chisso Corporation (JP) | 1991-01-23 | — | — | EP | disclosed |