Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325767 | 0.86 | KMT2A (0.77) | KMT2AMEN1ATMHSD17B10PIN1 | |
| SCHEMBL8134728 | 0.84 | USP2 (0.52) | KMT2AMEN1USP2HSD17B10GAA | |
| SCHEMBL9323617 | 0.84 | KMT2A (0.73) | KMT2AMEN1ATMPIN1PIN4 | |
| SCHEMBL6978730 | 0.81 | KMT2A (0.70) | KMT2AMEN1ATMHSD17B10PIN1 | |
| SCHEMBL8872431 | 0.81 | KMT2A (0.72) | KMT2AMEN1ATMGAAKDM4E | |
| SCHEMBL9323818 | 0.80 | KMT2A (0.76) | KMT2AMEN1ATMALDH1A1MAPT | |
| SCHEMBL9325709 | 0.79 | KMT2A (0.67) | KMT2AMEN1ATMKDM4EALDH1A1 | |
| SCHEMBL9322607 | 0.76 | KMT2A (0.76) | KMT2AMEN1ATMHSD17B10KDM4E | |
| SCHEMBL9323639 | 0.75 | KMT2A (0.65) | KMT2AMEN1ATMGAAPIN1 | |
| SCHEMBL8872080 | 0.75 | KMT2A (0.61) | KMT2AMEN1ATMHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353198-B1 | Parabanic acid derivatives and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1994-02-02 | — | — | EP | disclosed |
| US-4985453-A | DIABETES TREATMENT | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0353198-A1 | Parabanic acid derivatives and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1990-01-31 | — | — | EP | disclosed |