SCHEMBL9324074

SCHEMBL9324074

[O][SiH]([O])CCC1=CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
ALOX15 P16050 2/20 0.47
USP2 O75604 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TAAR1 Q96RJ0 1/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
NPC1 O15118 4/20 0.40
RAB9A P51151 4/20 0.40
MAPT P10636 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALOX12 P18054 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
HPGD P15428 1/20 0.40
EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28323674 0.79 ALDH1A1 (0.43) ALDH1A1ALOX15USP2NPSR1TAAR1
Water SCHEMBL28003772 0.78 ALDH1A1 (0.46) ALDH1A1ALOX15USP2NPSR1TAAR1
SCHEMBL8381260 0.77 ALDH1A1 (0.52) ALDH1A1ALOX15USP2NPSR1TAAR1
SCHEMBL2513477 0.77 ALDH1A1 (0.52) ALDH1A1ALOX15USP2NPSR1TAAR1
SCHEMBL953642 0.76
SCHEMBL8671709 0.75 ALDH1A1 (0.50) ALDH1A1ALOX15USP2NPSR1TAAR1
SCHEMBL5002876 0.75 ALDH1A1 (0.44) ALDH1A1ALOX15SMN1; SMN2NPC1RAB9A
SCHEMBL10596387 0.73 ALDH1A1 (0.42) ALDH1A1ALOX15USP2NPSR1SMN1; SMN2
SCHEMBL27628750 0.73 SMN1; SMN2 (0.49) ALDH1A1ALOX15USP2NPSR1TAAR1
SCHEMBL955333 0.72 ALDH1A1 (0.49) ALDH1A1ALOX15USP2NPSR1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0404029-B1 Substantially odor free, UV curable organopolysiloxane release coating compositions and coating method GEN ELECTRIC (US) 1994-02-16 EP disclosed
US-4994299-A Epoxyhaloarylaklsiloxane with polyaryloniumhexafluorometalloid salt photoinitiator GENERAL ELECTRIC COMPANY (US) 1991-02-19 US disclosed
EP-0404029-A1 Substantially odor free, UV curable organopolysiloxane release coating compositions and coating method GENERAL ELECTRIC COMPANY (US) 1990-12-27 EP disclosed