Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28003772 | 0.79 | ALDH1A1 (0.46) | ALDH1A1ALOX15RAB9APKMSMN1; SMN2 | |
| SCHEMBL5002876 | 0.76 | ALDH1A1 (0.44) | ALDH1A1ALOX15RAB9APKMSMN1; SMN2 | |
| SCHEMBL4989968 | 0.74 | ALDH1A1 (0.41) | ALDH1A1ALOX15RAB9APKMSMN1; SMN2 | |
| SCHEMBL28323674 | 0.73 | ALDH1A1 (0.43) | ALDH1A1ALOX15RAB9APKMSMN1; SMN2 | |
| SCHEMBL9324074 | 0.73 | ALDH1A1 (0.47) | ALDH1A1ALOX15RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3893406 | 0.71 | ALDH1A1 (0.40) | ALDH1A1ALOX15RAB9APKMSMN1; SMN2 | |
| SCHEMBL2513477 | 0.71 | ALDH1A1 (0.52) | ALDH1A1ALOX15RAB9APKMSMN1; SMN2 | |
| SCHEMBL8381260 | 0.71 | ALDH1A1 (0.52) | ALDH1A1ALOX15RAB9APKMSMN1; SMN2 | |
| SCHEMBL68781 | 0.70 | — | — | |
| SCHEMBL369943 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157540-B1 | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | Dow Corning Limited (GB) | 1989-01-11 | — | — | EP | disclosed |
| EP-0217333-A2 | Resinous copolymeric siloxanes containing alkenyldimethylsiloxanes | DOW CORNING CORPORATION (US) | 1987-04-08 | — | — | EP | disclosed |
| US-4587136-A | Curable organopolysiloxane compositions | DOW CORNING LTD. (GB) | 1986-05-06 | — | — | US | disclosed |
| EP-0157540-A2 | Curable organopolysiloxane compositions | Dow Corning Limited (GB) | 1985-10-09 | — | — | EP | disclosed |