SCHEMBL9324329

SCHEMBL9324329

CC(C)(C)c1cc(CCC=O)cc(-n2nc3ccccc3n2)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
POLB P06746 1/20 0.39
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
ALDH1A1 P00352 3/20 0.38
MAPT P10636 2/20 0.38
USP2 O75604 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
BLM P54132 1/20 0.38
ATM Q13315 1/20 0.38
HIF1A Q16665 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
LMNA P02545 1/20 0.37
GAA P10253 4/20 0.37
MAOB P27338 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13324689 0.85 NPC1 (0.44) NPC1RAB9APOLBMEN1KMT2A
SCHEMBL75075 0.85 NPC1 (0.44) NPC1RAB9APOLBMEN1KMT2A
SCHEMBL30240935 0.85 NPC1 (0.44) NPC1RAB9APOLBMEN1KMT2A
SCHEMBL3691311 0.83 NPC1 (0.40) NPC1RAB9APOLBMEN1KMT2A
SCHEMBL10135977 0.83 GAA (0.44) NPC1RAB9APOLBMEN1KMT2A
SCHEMBL100766 0.83 MAOB (0.45) NPC1RAB9APOLBMEN1KMT2A
SCHEMBL29768287 0.83 MAOB (0.45) NPC1RAB9APOLBMEN1KMT2A
SCHEMBL105358 0.83 NPC1 (0.42) NPC1RAB9APOLBMEN1KMT2A
SCHEMBL2955109 0.83 NPC1 (0.42) NPC1RAB9APOLBMEN1KMT2A
SCHEMBL5566811 0.82 GAA (0.43) NPC1RAB9APOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0342974-B1 Bisurea light stabilizer for organic polymers DU PONT (US) 1994-03-02 EP claimed
US-5233047-A Benzotriazole UV absorber hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-08-03 US claimed
US-5166234-A Ultraviolet radiation resistance; spandex E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-24 US claimed
EP-0342974-A1 Bisurea light stabilizer for organic polymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-11-23 EP claimed
US-11732167-B2 Silane-containing high modulus urethane adhesives DDP SPECIALTY ELECTRONIC MATERIALS US, LLC (US) 2023-08-22 US disclosed
CN-109071755-B Silane-containing high modulus polyurethane adhesive 陶氏环球技术有限责任公司 2021-12-07 CN disclosed
US-10874603-B2 Sunscreen compositions containing a UV-absorbing polyglycerol and a non-UV-absorbing polyglycerol JOHNSON & JOHNSON CONSUMER INC. (US) 2020-12-29 US disclosed
EP-3448903-B1 SILANE CONTAINING HIGH MODULUS URETHANE ADHESIVES DOW GLOBAL TECHNOLOGIES LLC (US) 2020-10-28 EP disclosed
EP-3127989-A1 LIQUID CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2017-02-08 EP disclosed
US-20160347956-A1 DIRT PICK-UP RESISTANT SILICONE COMPOSITIONS AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) 2016-12-01 US disclosed
US-20150320671-A1 SUNSCREEN COMPOSITIONS CONTAINING A UV-ABSORBING POLYGLYCEROL AND A NON-UV-ABSORBING POLYGLYCEROL KENVUE BRANDS LLC 2015-11-12 US disclosed
US-20150320671-A1 SUNSCREEN COMPOSITIONS CONTAINING A UV-ABSORBING POLYGLYCEROL AND A NON-UV-ABSORBING POLYGLYCEROL KENVUE BRANDS LLC 2015-11-12 US disclosed
EP-1670839-B1 STAIN RESISTANT POLYURETHANE COATINGS 3M INNOVATIVE PROPERTIES CO (US) 2014-01-29 EP disclosed
US-20130269875-A1 ALKOXYSILANE CONTAINING POLYURETHANE ADHESIVE COMPOSITIONS CONTAINING CALCIUM CARBONATE DOW GLOBAL TECHNOLOGIES LLC (US) 2013-10-17 US disclosed
US-8512421-B2 Polyurethane derivatives, composition thereof and dye additives comprising the polyurethane derivatives EVERLIGHT CHEMICAL INDUSTRIAL CORPORATION (TW) 2013-08-20 US disclosed
US-7901787-B2 Resin composite-type optical element and process for producing the resin composite-type optical element NIKON CORPORATION (JP) 2011-03-08 US disclosed
EP-0342974-B1 Bisurea light stabilizer for organic polymers DU PONT (US) 1994-03-02 EP disclosed
US-5166234-A Ultraviolet radiation resistance; spandex E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-24 US disclosed
US-5081258-A Spandex\ E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-14 US disclosed
EP-0342974-A1 Bisurea light stabilizer for organic polymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-11-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150320671-A1 SUNSCREEN COMPOSITIONS CONTAINING A UV-ABSORBING POLYGLYCEROL AND A NON-UV-ABSORBING POLYGLYCEROL DDOST, NOTUM, GGCT NPC1 616/4885RAB9A 2829/4885POLB 300/4885
US-10874603-B2 Sunscreen compositions containing a UV-absorbing polyglycerol and a non-UV-absorbing polyglycerol DDOST, NOTUM, GGCT NPC1 616/4885RAB9A 2829/4885POLB 300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.