SCHEMBL9324501

SCHEMBL9324501

CC(=O)ON(OCl)OC(C)=O

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.35
MEN1 O00255 1/20 0.31
ALOX15 P16050 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2001795 0.81 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL866389 0.81 ALDH1A1 (0.44) ALDH1A1TSHRMEN1ALOX15KMT2A
SCHEMBL29372767 0.78 ALDH1A1 (0.41) ALDH1A1TSHRMEN1ALOX15KMT2A
SCHEMBL28007094 0.78 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL10945928 0.78 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL29573344 0.78 ALDH1A1 (0.41) ALDH1A1TSHRMEN1ALOX15KMT2A
SCHEMBL22721070 0.78 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL7704495 0.73
SCHEMBL8010342 0.73 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL31147006 0.73 ALDH1A1 (0.37) ALDH1A1TSHRMEN1ALOX15KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0579810-A1 NOVEL PYRETHRINOID ESTERS DERIVED FROM ISOXAZOLIC OR ISOTHIAZOLIC ALCOHOL, PREPARATION METHOD THEREFOR AND USE THEREOF AS PESTICIDES ROUSSEL UCLAF (FR) 1994-01-26 EP disclosed
WO-1993016054-A1 NOVEL PYRETHRINOID ESTERS DERIVED FROM ISOXAZOLIC OR ISOTHIAZOLIC ALCOHOL, PREPARATION METHOD THEREFOR AND USE THEREOF AS PESTICIDES ROUSSEL-UCLAF (FR) 1993-08-19 WO disclosed