SCHEMBL9324544

SCHEMBL9324544

C[N+](C)(CCOCCOc1ccccc1)Cc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.70
MEN1 O00255 5/20 0.70
KMT2A Q03164 5/20 0.70
HTT P42858 5/20 0.70
LMNA P02545 4/20 0.70
ALDH1A1 P00352 4/20 0.70
TP53 P04637 4/20 0.70
TSHR P16473 3/20 0.70
TDP1 Q9NUW8 3/20 0.70
APAF1 O14727 3/20 0.70
USP2 O75604 3/20 0.70
MAPT P10636 3/20 0.70
RAD52 P43351 3/20 0.70
CHRM2 P08172 3/20 0.70
ADRA2A P08913 3/20 0.70
CHRM1 P11229 3/20 0.70
ADRA2B P18089 3/20 0.70
ADRA2C P18825 3/20 0.70
CHRM3 P20309 3/20 0.70
SLC6A2 P23975 3/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5156049 0.98 SMN1; SMN2 (0.70) SMN1; SMN2MEN1KMT2AHTTLMNA
Bephenium SCHEMBL44590 0.90 CHRM2 (0.58) SMN1; SMN2MEN1KMT2AHTTLMNA
Bephenium SCHEMBL9181734 0.88 SMN1; SMN2 (0.59) SMN1; SMN2MEN1KMT2AHTTLMNA
Bephenium SCHEMBL9118297 0.88 HTT (0.58) SMN1; SMN2MEN1KMT2AHTTLMNA
SCHEMBL13406736 0.88 CHRM2 (0.60) SMN1; SMN2MEN1KMT2AHTTLMNA
SCHEMBL19916799 0.87 KMT2A (0.78) SMN1; SMN2MEN1KMT2AHTTLMNA
SCHEMBL16353091 0.85 SMN1; SMN2 (0.74) SMN1; SMN2MEN1KMT2AHTTLMNA
Hydrochloric Acid SCHEMBL10939133 0.85 MEN1 (0.63) SMN1; SMN2MEN1KMT2AHTTLMNA
SCHEMBL9180609 0.85 DNM1 (0.59) SMN1; SMN2MEN1KMT2AHTTLMNA
Hydrochloric Acid SCHEMBL7072834 0.84 TP53 (0.61) SMN1; SMN2MEN1KMT2AHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0579729-A1 QUATERNARY AMMONIUM ANTIBACTERIAL DENTIFRICES WITH SELECTED CALCIUM ABRASIVES SMITHKLINE BEECHAM CORPORATION (US) 1994-01-26 EP disclosed