Bephenium

Bephenium

SCHEMBL44590

C[N+](C)(CCOc1ccccc1)Cc1ccccc1

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 3/20 0.58
ADRA2A P08913 3/20 0.58
CHRM1 P11229 3/20 0.58
ADRA2B P18089 3/20 0.58
ADRA2C P18825 3/20 0.58
CHRM3 P20309 3/20 0.58
SLC6A2 P23975 3/20 0.58
HTR2A P28223 3/20 0.58
HTR2C P28335 3/20 0.58
SLC6A4 P31645 3/20 0.58
SLC6A3 Q01959 3/20 0.58
KCNH2 Q12809 3/20 0.58
MLNR O43193 2/20 0.58
NR1I2 O75469 2/20 0.58
ESR1 P03372 2/20 0.58
NR3C1 P04150 2/20 0.58
PGR P06401 2/20 0.58
ADRB2 P07550 2/20 0.58
ADRB1 P08588 2/20 0.58
HTR1A P08908 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bephenium SCHEMBL9118297 0.98 HTT (0.58) CHRM2ADRA2ACHRM1ADRA2BADRA2C
Bephenium SCHEMBL9181734 0.98 SMN1; SMN2 (0.59) CHRM2ADRA2ACHRM1ADRA2BADRA2C
SCHEMBL9180609 0.91 DNM1 (0.59) CHRM2ADRA2ACHRM1ADRA2BADRA2C
SCHEMBL9324544 0.90 SMN1; SMN2 (0.70) CHRM2ADRA2ACHRM1ADRA2BADRA2C
Hydrochloric Acid SCHEMBL9179821 0.89 MEN1 (0.60) CHRM2ADRA2ACHRM1ADRA2BADRA2C
Hydrochloric Acid SCHEMBL5156049 0.89 SMN1; SMN2 (0.70) CHRM2ADRA2ACHRM1ADRA2BADRA2C
SCHEMBL9187376 0.84 CHRM2 (0.50) CHRM2ADRA2ACHRM1ADRA2BADRA2C
SCHEMBL9539266 0.84 ALOX5 (0.54) CHRM2ADRA2ACHRM1ADRA2BADRA2C
SCHEMBL24465407 0.82 CHRNA7 (0.65) CHRM2ADRA2ACHRM1ADRA2BADRA2C
SCHEMBL19912115 0.81 CHRM2 (0.62) CHRM2ADRA2ACHRM1ADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1562 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4586826-A1 FEED AND METHODS FOR CONTROLLING HEARTWORM INFECTIONS IN A MAMMAL In the Bowl Animal Health, Inc. (US) 2025-07-23 EP claimed
US-12295957-B2 Ascorbic acid and quinone compounds in combination with an antiparasitic agent for treating a parasitic disease IC-MedTech Corp. (US) 2025-05-13 US claimed
WO-2024264012-A1 BIOAVAILABILITY ENHANCING IONIC LIQUID FORMULATIONS INCLUDING ANTHELMINITIC BENZIMIDAZOLE COMPOUNDS AND USES THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2024-12-26 WO claimed
WO-2024264013-A1 BIOAVAILABILITY ENHANCING IONIC LIQUID FORMULATIONS AND USES THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2024-12-26 WO claimed
US-20240165084-A1 ASCORBIC ACID AND QUINONE COMPOUNDS IN COMBINATION WITH AN ANTIPARASITIC AGENT FOR TREATING A PARASITIC DISEASE IC-MedTech Corp. 2024-05-23 US claimed
WO-2024059837-A1 FEED AND METHODS FOR CONTROLLING HEARTWORM INFECTIONS IN A MAMMAL IN THE BOWL ANIMAL HEALTH, INC. (US) 2024-03-21 WO claimed
US-11872233-B2 Ascorbic acid and quinone compounds in combination with an antiparasitic agent for treating a parasitic disease IC-MedTech Corp. (US) 2024-01-16 US claimed
US-20210361666-A1 ASCORBIC ACID AND QUINONE COMPOUNDS IN COMBINATION WITH AN ANTIPARASITIC AGENT FOR TREATING A PARASITIC DISEASE MARINGA STATE UNIVERSITY (BR) 2021-11-25 US claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-8147561-B2 Methods and devices to curb appetite and/or reduce food intake ENDOSPHERE, INC. (US) 2012-04-03 US claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20060178691-A1 Methods and devices to curb appetite and/or reduce food intake THE DIRECTOR OF DEVELOPMENT OF THE STATE OF OHIO 2006-08-10 US claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
EP-0606756-B1 Use of disulfonyl methanes for the control of parasites LILLY CO ELI (US) 1997-07-23 EP claimed
US-5614525-A ANTHELMINTICS ELI LILLY AND COMPANY (US) 1997-03-25 US claimed
EP-0507629-B1 Sustained release capsule and formulations for insertion into rumen LILLY CO ELI (US) 1997-01-22 EP claimed
EP-0549773-B1 ETHER-CONTAINING QUATERNARY AMMONIUM SALTS EASTMAN KODAK CO (US) 1995-07-05 EP claimed
CN-1094225-A Prevent and treat the bephenium missible oil of resistance aphid SUN CHENGJUN (CN) 1994-11-02 CN claimed
EP-0606756-A1 Use of disulfonyl methanes for the control of parasites ELI LILLY AND COMPANY (US) 1994-07-20 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11872233-B2 Ascorbic acid and quinone compounds in combination with an antiparasitic agent for treating a parasitic disease NQO1, ADH7, CYP27B1 CHRM2 1443/4885ADRA2A 1259/4885CHRM1 1311/4885
US-20210361666-A1 ASCORBIC ACID AND QUINONE COMPOUNDS IN COMBINATION WITH AN ANTIPARASITIC AGENT FOR TREATING A PARASITIC DISEASE NQO1, ADH7, CYP27B1 CHRM2 1443/4885ADRA2A 1259/4885CHRM1 1311/4885
US-20240165084-A1 ASCORBIC ACID AND QUINONE COMPOUNDS IN COMBINATION WITH AN ANTIPARASITIC AGENT FOR TREATING A PARASITIC DISEASE NQO1, ADH7, CYP27B1 CHRM2 1443/4885ADRA2A 1259/4885CHRM1 1311/4885
US-12295957-B2 Ascorbic acid and quinone compounds in combination with an antiparasitic agent for treating a parasitic disease NQO1, ADH7, CYP27B1 CHRM2 1443/4885ADRA2A 1259/4885CHRM1 1311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.