Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765988 | 0.90 | NPSR1 (0.39) | NPSR1HTTLMNAL3MBTL1CYP3A4 | |
| SCHEMBL9326834 | 0.86 | NPSR1 (0.39) | NPSR1HTTLMNAL3MBTL1ALOX12 | |
| SCHEMBL9325707 | 0.77 | CYP2E1 (0.35) | CYP3A4CYP2C9CYP2C19CYP2E1CYP2A6 | |
| SCHEMBL9326720 | 0.76 | NPSR1 (0.40) | NPSR1HTTLMNAL3MBTL1GAA | |
| SCHEMBL9324700 | 0.76 | TP53 (0.39) | NPSR1HTTLMNAL3MBTL1CYP2A6 | |
| SCHEMBL9431991 | 0.75 | NPSR1 (0.40) | NPSR1HTTLMNAL3MBTL1ALOX12 | |
| SCHEMBL9326821 | 0.75 | NPSR1 (0.37) | NPSR1HTTLMNAL3MBTL1ALOX12 | |
| SCHEMBL9327773 | 0.73 | NPSR1 (0.38) | NPSR1HTTLMNAL3MBTL1GAA | |
| SCHEMBL9325735 | 0.71 | ADRA2A (0.42) | NPSR1CYP3A4CYP2C9CYP2C19CYP2E1 | |
| SCHEMBL9325689 | 0.69 | CYP2E1 (0.35) | CYP3A4CYP2C9CYP2C19CYP2E1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372954-B1 | Substituted imidazole derivatives and their preparation and use | ORION YHTYMAE OY (FI) | 1994-03-09 | — | — | EP | claimed |
| US-5292887-A | Antgonists at postsynoptic adrenoreceptors; hypotensive and antidiabetic agents | FARMOS-YHTYMA OY (FI) | 1994-03-08 | — | — | US | claimed |
| US-5292887-A | Antgonists at postsynoptic adrenoreceptors; hypotensive and antidiabetic agents | FARMOS-YHTYMA OY (FI) | 1994-03-08 | — | — | US | disclosed |