Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9324661 | 0.91 | NPSR1 (0.40) | NPSR1HTTLMNAL3MBTL1GAA | |
| SCHEMBL9326821 | 0.87 | NPSR1 (0.37) | NPSR1HTTLMNAL3MBTL1GAA | |
| SCHEMBL9327660 | 0.79 | NPSR1 (0.38) | NPSR1HTTLMNAL3MBTL1GAA | |
| SCHEMBL9326834 | 0.77 | NPSR1 (0.39) | NPSR1HTTLMNAL3MBTL1GAA | |
| SCHEMBL9324708 | 0.73 | NPSR1 (0.38) | NPSR1HTTLMNAL3MBTL1GAA | |
| SCHEMBL9431991 | 0.72 | NPSR1 (0.40) | NPSR1HTTLMNAL3MBTL1GAA | |
| SCHEMBL31034847 | 0.72 | ADRA2A (0.50) | NPSR1ALDH1A1HTR2CIDO1 | |
| SCHEMBL9325913 | 0.72 | ADRA2A (0.50) | NPSR1ALDH1A1HTR2CIDO1 | |
| SCHEMBL13253339 | 0.71 | NPSR1 (0.57) | NPSR1HTTLMNAL3MBTL1GAA | |
| SCHEMBL9326720 | 0.71 | NPSR1 (0.40) | NPSR1HTTLMNAL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372954-B1 | Substituted imidazole derivatives and their preparation and use | ORION YHTYMAE OY (FI) | 1994-03-09 | — | — | EP | claimed |
| US-5292887-A | Antgonists at postsynoptic adrenoreceptors; hypotensive and antidiabetic agents | FARMOS-YHTYMA OY (FI) | 1994-03-08 | — | — | US | claimed |
| US-5292887-A | Antgonists at postsynoptic adrenoreceptors; hypotensive and antidiabetic agents | FARMOS-YHTYMA OY (FI) | 1994-03-08 | — | — | US | disclosed |