Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9571171 | 0.82 | HPGD (0.49) | HPGDCYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL9571201 | 0.80 | HPGD (0.47) | HPGDCYP1A2CYP3A4CYP2C19RAB9A | |
| SCHEMBL9325794 | 0.80 | HPGD (0.47) | HPGDCYP1A2CYP3A4CYP2C19RAB9A | |
| SCHEMBL9314085 | 0.80 | ESR1 (0.37) | HPGDSMN1; SMN2TSHRKMT2AUSP2 | |
| SCHEMBL9571196 | 0.79 | HPGD (0.49) | HPGDCYP1A2CYP3A4CYP2C19RAB9A | |
| SCHEMBL9571177 | 0.79 | HPGD (0.46) | HPGDCYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL9313686 | 0.79 | KDM4E (0.41) | SMN1; SMN2KMT2AUSP2NPSR1MAPT | |
| SCHEMBL9571180 | 0.77 | HPGD (0.44) | HPGDCYP1A2CYP3A4CYP2C19TSHR | |
| SCHEMBL10846099 | 0.75 | RAB9A (0.74) | HPGDCYP1A2CYP2C19RAB9ASMN1; SMN2 | |
| SCHEMBL9587283 | 0.72 | RAB9A (0.52) | HPGDRAB9ASMN1; SMN2KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553630-A1 | Pyridyloxy-naphthalines as herbicides | BAYER AG (DE) | 1993-08-04 | — | — | EP | claimed |
| JP-6092936-A | — | — | None | — | — | JP | disclosed |
| JP-H0692936-A | PYRIDYLOXY-NAPHTHALENES | BAYER AG | 1994-04-05 | — | — | JP | disclosed |
| EP-0553630-A1 | Pyridyloxy-naphthalines as herbicides | BAYER AG (DE) | 1993-08-04 | — | — | EP | disclosed |