Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.38 |
| ▸ | BRAF | P15056 | 4/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644001 | 0.84 | STK39 (0.47) | STK39ESR1ESR2 | |
| SCHEMBL9314085 | 0.84 | ESR1 (0.37) | MAPTNPSR1SCN8ASCN10AMEN1 | |
| SCHEMBL9643981 | 0.79 | ESR1 (0.41) | MAPTNPSR1L3MBTL1BRAFMEN1 | |
| SCHEMBL9324852 | 0.79 | HPGD (0.54) | KDM4EMAPTNPSR1L3MBTL1MEN1 | |
| SCHEMBL9520497 | 0.78 | CCR1 (0.39) | TRPA1MAPTNPSR1L3MBTL1SCN8A | |
| SCHEMBL9315073 | 0.77 | PTGDR2 (0.51) | SCN8ASCN10AKMT2A | |
| SCHEMBL9617276 | 0.77 | PTGDR2 (0.51) | SCN8ASCN10AKMT2A | |
| SCHEMBL9313717 | 0.76 | PTGDR2 (0.41) | NPSR1SCN8ASCN10ABRAF | |
| SCHEMBL9710658 | 0.76 | AR (0.42) | KDM4ETRPA1MAPTNPSR1MEN1 | |
| SCHEMBL9313708 | 0.76 | F9 (0.43) | NPSR1SCN8ASCN10ABRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300676-A | Herbicidal fluorine-substituted alpha-(5-aryloxynaphthalen-1-yl-oxy)-propionic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| EP-0508263-A2 | Derivatives of alpha-(5 aryloxy-1 naphthyloxy)-carboxylic acid | BAYER AG (DE) | 1992-10-14 | — | — | EP | disclosed |
| EP-0453842-A2 | Fluor subsituted derivatives of alpha-(5-aryloxy-naphthalen-1-yloxy)propionic acid | BAYER AG (DE) | 1991-10-30 | — | — | EP | disclosed |