Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347119 | 0.81 | MAPT (0.42) | HPGDNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL4735612 | 0.78 | ALDH1A1 (0.54) | HPGDNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL1995924 | 0.78 | ALDH1A1 (0.42) | HPGDALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL334956 | 0.75 | KMT2A (0.47) | HPGDALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL30177551 | 0.75 | ALDH1A1 (0.50) | HPGDNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL496788 | 0.75 | HTT (0.55) | HPGDALDH1A1MAPTKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL7763898 | 0.74 | KMT2A (0.46) | HPGDALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL13508575 | 0.74 | KDM4E (0.45) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29818200 | 0.74 | KDM4E (0.45) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL31054164 | 0.73 | MAPT (0.48) | HPGDALDH1A1MAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339976-B1 | Anti-tumour agents | ICI PLC (GB) | 1994-02-02 | — | — | EP | disclosed |