Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991923 | 0.84 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDTSHRFOLH1 | |
| SCHEMBL6445972 | 0.84 | FOLH1 (0.59) | ALDH1A1KDM4EHPGDTSHRFOLH1 | |
| SCHEMBL4735612 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL28316789 | 0.82 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL13508575 | 0.81 | KDM4E (0.45) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL29818200 | 0.81 | KDM4E (0.45) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL334956 | 0.79 | KMT2A (0.47) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL28890207 | 0.79 | AKR1C3 (0.47) | ALDH1A1KDM4EMAPTTSHRFOLH1 | |
| SCHEMBL30177551 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL9324897 | 0.78 | HPGD (0.43) | ALDH1A1KDM4EMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140213557-A1 | Active Compound Combinations | BAYER CROPSCIENCE AG (DE) | 2014-07-31 | — | — | US | claimed |
| US-9414600-B2 | Active compound combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-08-16 | — | — | US | disclosed |
| US-20140213557-A1 | Active Compound Combinations | BAYER CROPSCIENCE AG (DE) | 2014-07-31 | — | — | US | disclosed |
| US-8754009-B2 | Active compound combinations | BAYER CROPSCIENCE AG (DE) | 2014-06-17 | — | — | US | disclosed |
| US-20110152097-A1 | Active Compound Combinations | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152097-A1 | Active Compound Combinations | AGXT, GLUL, GMNN | ALDH1A1 4519/4885KDM4E 2720/4885MAPT 415/4885 |
| US-20140213557-A1 | Active Compound Combinations | AGXT, GLUL, GMNN | ALDH1A1 4519/4885KDM4E 2720/4885MAPT 415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.