SCHEMBL9324946

SCHEMBL9324946

Nc1ccccc1P(c1ccccc1)c1ccccc1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.52
TDP1 Q9NUW8 2/20 0.52
ALOX15 P16050 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
ALDH1A1 P00352 5/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
HSD17B10 Q99714 3/20 0.37
GAA P10253 3/20 0.37
KDM4E B2RXH2 3/20 0.37
DRD1 P21728 2/20 0.36
TSHR P16473 4/20 0.35
MEN1 O00255 3/20 0.33
MAPT P10636 3/20 0.33
KMT2A Q03164 3/20 0.33
NPC1 O15118 2/20 0.33
CYP1A2 P05177 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5403788 0.95 CYP3A4 (0.52) CYP3A4TDP1ALOX15SMN1; SMN2CASP1
SCHEMBL29620625 0.95 CYP3A4 (0.52) CYP3A4TDP1ALOX15SMN1; SMN2CASP1
Iodide SCHEMBL8511390 0.93 CYP3A4 (0.50) CYP3A4TDP1ALOX15SMN1; SMN2CASP1
Bromide SCHEMBL17963057 0.93 CYP3A4 (0.50) CYP3A4TDP1ALOX15SMN1; SMN2CASP1
SCHEMBL3064055 0.84 CYP3A4 (0.53) CYP3A4TDP1ALOX15SMN1; SMN2CASP1
SCHEMBL31193487 0.79 CYP3A4 (0.46) CYP3A4TDP1ALOX15SMN1; SMN2CASP1
SCHEMBL8073956 0.78 CYP3A4 (0.65) CYP3A4TDP1ESR1ESR2ALDH1A1
SCHEMBL30842821 0.78 ALDH1A1 (0.54) CYP3A4TDP1ALOX15SMN1; SMN2CASP1
SCHEMBL30842815 0.78 ALDH1A1 (0.54) CYP3A4TDP1ALOX15SMN1; SMN2CASP1
SCHEMBL29230460 0.78 ALDH1A1 (0.54) CYP3A4TDP1ALOX15SMN1; SMN2CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6093099-A None JP disclosed
JP-H0693099-A AROMATIC COPOLYAMIDE TOKUYAMA SODA CO LTD 1994-04-05 JP disclosed
EP-0218100-B1 CONJUGATED ALKADIENE TELOMERIZATION TO ORGANO-OXYALKADIENES QUANTUM CHEMICAL CORPORATION (a Virginia corp.) (US) 1989-11-29 EP disclosed
EP-0218100-A1 Conjugated alkadiene telomerization to organo-oxyalkadienes QUANTUM CHEMICAL CORPORATION (a Virginia corp.) (US) 1987-04-15 EP disclosed