SCHEMBL9324952

SCHEMBL9324952

Nc1ccccc1-c1cccc(P)c1-c1ccccc1N

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
HSD17B10 Q99714 3/20 0.44
ADORA2A P29274 2/20 0.42
PTPRC P08575 1/20 0.42
CYP3A4 P08684 4/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
ALOX15 P16050 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
IDO1 P14902 4/20 0.38
FGR P09769 1/20 0.37
PIM1 P11309 1/20 0.37
MAOA P21397 1/20 0.37
CSNK1A1 P48729 1/20 0.37
CSNK1D P48730 1/20 0.37
DYRK1A Q13627 1/20 0.37
HIPK2 Q9H2X6 1/20 0.37
CSNK1G1 Q9HCP0 1/20 0.37
HSPA1A P0DMV8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3714036 0.85 ALDH1A1 (0.72) ALDH1A1L3MBTL1HSD17B10ADORA2APTPRC
SCHEMBL16091754 0.83 ALDH1A1 (0.68) ALDH1A1L3MBTL1HSD17B10ADORA2APTPRC
SCHEMBL5493737 0.83 ALDH1A1 (0.68) ALDH1A1L3MBTL1HSD17B10ADORA2APTPRC
SCHEMBL6535680 0.78 ALDH1A1 (0.39) ALDH1A1L3MBTL1HSD17B10ADORA2APTPRC
SCHEMBL7389021 0.78 ALDH1A1 (0.67) ALDH1A1L3MBTL1HSD17B10ADORA2APTPRC
SCHEMBL169281 0.77 ALDH1A1 (1.00) ALDH1A1L3MBTL1HSD17B10ADORA2APTPRC
SCHEMBL31607672 0.77 ALDH1A1 (1.00) ALDH1A1L3MBTL1HSD17B10ADORA2APTPRC
SCHEMBL2490795 0.76 ALDH1A1 (0.56) ALDH1A1L3MBTL1HSD17B10ADORA2APTPRC
Ammonia Solution, Strong SCHEMBL21297045 0.74 ALDH1A1 (0.93) ALDH1A1L3MBTL1HSD17B10ADORA2APTPRC
Hydrochloric Acid SCHEMBL21465353 0.74 ALDH1A1 (0.93) ALDH1A1L3MBTL1HSD17B10ADORA2APTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6093099-A None JP disclosed
JP-H0693099-A AROMATIC COPOLYAMIDE TOKUYAMA SODA CO LTD 1994-04-05 JP disclosed
EP-0218100-B1 CONJUGATED ALKADIENE TELOMERIZATION TO ORGANO-OXYALKADIENES QUANTUM CHEMICAL CORPORATION (a Virginia corp.) (US) 1989-11-29 EP disclosed
EP-0218100-A1 Conjugated alkadiene telomerization to organo-oxyalkadienes QUANTUM CHEMICAL CORPORATION (a Virginia corp.) (US) 1987-04-15 EP disclosed