Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | BRAF | P15056 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325166 | 1.00 | RAB9A (0.53) | RAB9ANPC1BRAFMAPTGAA | |
| SCHEMBL7062015 | 0.81 | RAB9A (0.57) | RAB9ANPC1MAPTGAASMN1; SMN2 | |
| SCHEMBL29282943 | 0.78 | NR1H4 (0.54) | RAB9ANPC1BRAFMAPTSMN1; SMN2 | |
| SCHEMBL523154 | 0.76 | KMT2A (0.67) | RAB9ANPC1MAPTCRHBPCRHR2 | |
| SCHEMBL87044 | 0.75 | POLB (0.61) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL10584067 | 0.74 | CYP1B1 (0.52) | RAB9ANPC1MAPTCYP1B1MEN1 | |
| SCHEMBL9179899 | 0.74 | NPC1 (0.49) | RAB9ANPC1BRAFMAPTSMN1; SMN2 | |
| SCHEMBL6966891 | 0.74 | PLAU (0.59) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL29566162 | 0.73 | KMT2A (0.65) | RAB9ANPC1MAPTSMN1; SMN2TAAR1 | |
| SCHEMBL4656414 | 0.73 | SLC6A2 (0.53) | RAB9ANPC1SMN1; SMN2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326762-A | Heterocyclic substituted amides | SCHERING CORPORATION (US) | 1994-07-05 | — | — | US | disclosed |
| US-5149709-A | Treatment of atherosclerosis | SCHERING CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |