Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942377 | 0.84 | LMNA (0.59) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5845871 | 0.84 | NR4A1 (0.51) | RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL7450597 | 0.82 | CTRB1 (0.49) | RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL6655085 | 0.81 | PLAU (0.49) | RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL8363489 | 0.81 | NPC1 (0.50) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7442011 | 0.81 | ALDH1A1 (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL9325161 | 0.81 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2MAPTGAA | |
| SCHEMBL9325166 | 0.81 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2MAPTGAA | |
| SCHEMBL7276193 | 0.80 | LMNA (0.55) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL8407251 | 0.80 | SRD5A2 (0.48) | SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102746-B1 | SUBSTITUTED PHENYLAMIDINES WITH ANTITHROMBOTIC ACTION | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-05-14 | — | — | EP | disclosed |
| EP-1102746-A1 | SUBSTITUTED PHENYLAMIDINES WITH ANTITHROMBOTIC ACTION | BOEHRINGER INGELHEIM KG (DE) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000005207-A1 | SUBSTITUTED PHENYLAMIDINES WITH ANTITHROMBOTIC ACTION | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-02-03 | — | — | WO | disclosed |